| Tag | Content |
|---|
| CPLM ID | CPLM-015874 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transcription factor SPT20 homolog |
Protein Synonyms/Alias | p38-interacting protein; p38IP |
Gene Name | Supt20h |
Gene Synonyms/Alias | D3Ertd300e; Fam48a; Supt20 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 497 | PTPPPSCKPSLSRKS | acetylation | [1] |
|
Reference | [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways. Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y. Mol Cell. 2013 Jun 27;50(6):919-30. [ PMID: 23806337] |
Functional Description | Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down- regulation of E-cadherin during gastrulation by regulating E- cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy. |
Sequence Annotation | MOD_RES 515 515 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Developmental protein; Gastrulation; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 530 AA |
Protein Sequence | MQQAVEQALD CAEYIVESAQ QRPPKRKYLS SGRKSIFQKL YDLYVEECEK EPEVKKLRRN 60
VNLLEKLVMQ ETLSCLVVNL YPGNEGYSLM LRGKNGSDSE TIRLPYEEGE LLEYLDAEEL 120
PPILVDLLEK SQVNIFHCGC VIAEIRDYRQ SSNMKSPGYQ SRHILLRPTM QTLVCDVHSI 180
TSDNHKWTQE DKLLLESQLI LATAEPLCLD PSVAVACTAN RLLYNRQKMN TRPMKRCWKR 240
YSRSSLNRQQ DLSHGPPPPQ LRLLDFLQKR KERKAGQHYD LKISKAGNCV DMWKRSPCNL 300
AVPSEVDVEK YAKVEESIKS DDSQPTMWPA HDVKDDYVFE CEGGNQYQKT KLTILQSLGD 360
PLYYGKIQPW KADEENDSQM SPSHSSADDH SNWFVIGSKT DAERVVNQYQ ELVQNEAKCP 420
VKMSHSSSGS AALSPGEEAE QAETSSIQSS VLGKGVKHRP PPIKLPSGSG NSSSGNYFTA 480
QQASSFLKSP TPPPSCKPSL SRKSSVDLSQ VSMLSPAALS PASSSQRHES 530 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |