CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005450
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 High frequency lysogenization protein HflD 
Protein Synonyms/Alias
  
Gene Name
 hflD 
Gene Synonyms/Alias
 ycfC; b1132; JW5165 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
203NRLTTQAKQILAHLTacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Negative regulator of phage lambda lysogenization. Contributes to the degradation of the phage regulatory protein CII. Acts probably by holding CII on the membrane surface, away from the target promoters, but close to the FtsH protease. 
Sequence Annotation
  
Keyword
 3D-structure; Cell inner membrane; Cell membrane; Coiled coil; Complete proteome; Cytoplasm; Membrane; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 213 AA 
Protein Sequence
MAKNYYDITL ALAGICQSAR LVQQLAHQGH CDADALHVSL NSIIDMNPSS TLAVFGGSEA 60
NLRVGLETLL GVLNASSRQG LNAELTRYTL SLMVLERKLS SAKGALDTLG NRINGLQRQL 120
EHFDLQSETL MSAMAAIYVD VISPLGPRIQ VTGSPAVLQS PQVQAKVRAT LLAGIRAAVL 180
WHQVGGGRLQ LMFSRNRLTT QAKQILAHLT PEL 213 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:EcoCyc.
 GO:0009408; P:response to heat; IEP:EcoliWiki. 
Interpro
 IPR007451; UPF0274. 
Pfam
 PF04356; DUF489 
SMART
  
PROSITE
  
PRINTS