CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035128
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 
Protein Synonyms/Alias
  
Gene Name
 Cacna1a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1467IRTALDIKIAKGGADacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Calcium channel; Calcium transport; Complete proteome; Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane; Transport; Voltage-gated channel. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1819 AA 
Protein Sequence
MEWISKAEEV ILAEDETDVE QRHPFDGALR RATLKKSKTD LLNPEEAEDQ LADIASVGSP 60
FARASIKSAK LENSTFFHKK ERRMRFYIRR MVKTQAFYWT VLSLVALNTL CVAIVHYNQP 120
EWLSDFLYYA EFIFLGLFMS EMFIKMYGLG TRPYFHSSFN CFDCGVIIGS IFEVIWAVIK 180
PGTSFGISVL RALRLLRIFK VTKYWASLRN LVVSLLNSMK SIISLLFLLF LFIVVFALLG 240
MQLFGGQFNF DEGTPPTNFD TFPAAIMTVF QILTGEDWNE VMYDGIKSQG GVQGGMVFSI 300
YFIVLTLFGN YTLLNVFLAI AVDNLANAQE LTKDEQEEEE AANQKLALQK AKEVAEVSPL 360
SAANMSIAVK EQQKNQKPAK SVWEQRTSEM RKQNLLASRE ALYGDAAERW PTTYARPLRP 420
DVKTHLDRPL VVDPQENRNN NTNKSRAPEA LRQTARPRES ARDPDARRAW PSSPERAPGR 480
EGPYGRESEP QQREHAPPRE HVPWDADPER AKAGDAPRRH THRPVAEGEP RRHRARRRPG 540
DEPDDRPERR PRPRDATRPA RAADGEGDDG ERKRRHRHGP PAHDDRERRH RRRKESQGSG 600
VPMSGPNLST TRPIQQDLGR QDLPLAEDLD NMKNNKLATG EPASPHDSLG HSGLPPSPAK 660
IGNSTNPGPA LATNPQNAAS RRTPNNPGNP SNPGPPKTPE NSLIVTNPSS TQPNSAKTAR 720
KPEHMAVEIP PACPPLNHTV VQVNKNANPD PLPKKEEEKK EEEEADPGED GPKPMPPYSS 780
MFILSTTNPL RRLCHYILNL RYFEMCILMV IAMSSIALAA EDPVQPNAPR NNVLRYFDYV 840
FTGVFTFEMV IKMIDLGLVL HQGAYFRDLW NILDFIVVSG ALVAFAFTGN SKGKDINTIK 900
SLRVLRVLRP LKTIKRLPKL KAVFDCVVNS LKNVFNILIV YMLFMFIFAV VAVQLFKGKF 960
FHCTDESKEF ERDCRGKYLL YEKNEVKARD REWKKYDFHY DNVLWALLTL FTVSTGEGWP 1020
QVLKHSVDAT FENQGPSPGY RMEMSIFYVV YFVVFPFFFV NIFVALIIIT FQEQGDKMME 1080
EYSLEKNERA CIDFAISAKP LTRHMPQNKQ SFQYRMWQFV VSPPFEYTIM AMIALNTIVL 1140
MMKTPSPSLG DSRSSLYNSQ VFLSLFKMPV PNSVMSWGLE NYFRDAWNIF DFVTVLGSIT 1200
DILVTEFGNP NNFINLSFLR LFRAARLIKL LRQGYTIRIL LWTFVQSFKA LPYVCLLIAM 1260
LFFIYAIIGM QVFGNIGIDG EDEDSDEDEF QITEHNNFRT FFQALMLLFR SATGEAWHNI 1320
MLSCLSGKPC DKNSGIQKPE CGNEFAYFYF VSFIFLCSFL MLNLFVAVIM DNFEYLTRDS 1380
SILGPHHLDE YVRVWAEYDP AACGRIHYKD MYSLLRVISP PLGLGKKCPH RVACKRLLRM 1440
DLPVADDNTV HFNSTLMALI RTALDIKIAK GGADKQQMDA ELRKEMMAIW PNLSQKTLDL 1500
LVTPHKSTDL TVGKIYAAMM IMEYYRQSKA KKLQAMREEQ NRTPLMFQRM EPPSPTQEGG 1560
PSQNALPSTQ LDPGGGLMAQ ESSMKESPSW VTQRAQEMFQ KTGTWSPERG PPIDMPNSQP 1620
NSQSVEMREM GTDGYSDSEH YLPMEGQTRA ASMPRLPAEN QRRRGRPRNN LTTISDTSPM 1680
KRSASVLGPK ARRLDDYSLE RVPPEENQRY HQRRRDRGHR TSERSLGRYT DVDTGLGTDL 1740
SMTTQSGDLP SKDRDQDRGR PKDRKHRPHH HHHHHHHHPP APDRERYAQE RPDTGRARAR 1800
EQRWSRSPSE GREHATHRQ 1819 
Gene Ontology
 GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
 GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. 
Interpro
 IPR005821; Ion_trans_dom.
 IPR027359; K_channel_four-helix_dom.
 IPR014873; VDCC_a1su_IQ.
 IPR005448; VDCC_P/Q_a1su.
 IPR002077; VDCCAlpha1. 
Pfam
 PF08763; Ca_chan_IQ
 PF00520; Ion_trans 
SMART
 SM01062; Ca_chan_IQ 
PROSITE
  
PRINTS
 PR00167; CACHANNEL.
 PR01632; PQVDCCALPHA1.