UniProt Accession

 FUT7_HUMAN; Q11130; B2R7U7; Q6DK54 

Genbank Protein ID

 X78031; U11282; U08112; AB012668; AK313124; AL807752; BC074746; BC086312 

Genbank Nucleotide ID

 CAA54962.1; AAA20468.1; AAA56869.1; BAA32819.1; BAG35944.1; CAI12771.1; AAH74746.2; AAH86312.1 

Protein Name

 Alpha-(1,3)-fucosyltransferase 

Protein Synonyms/Alias

 Fucosyltransferase 7; Fucosyltransferase VII; Fuc-TVII; FucT-VII; Galactoside 3-L-fucosyltransferase; Selectin ligand synthase 

Gene Name

 FUT7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
240	HRDYITEKFWRNALV	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens. 

Sequence Annotation

 CARBOHYD 81 81 N-linked (GlcNAc...) (Potential).
 CARBOHYD 291 291 N-linked (GlcNAc...) (Potential).
 DISULFID 68 76
 DISULFID 211 214
 DISULFID 318 321  

Keyword

 Complete proteome; Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus; Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 342 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; TAS:UniProtKB.
 GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; TAS:ProtInc.
 GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; TAS:UniProtKB.
 GO:0002361; P:CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IEA:Compara.
 GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
 GO:0002522; P:leukocyte migration involved in immune response; IEA:Compara.
 GO:0006486; P:protein glycosylation; TAS:UniProtKB. 

Interpro

 IPR001503; Glyco_trans_10. 

Pfam

 PF00852; Glyco_transf_10 

SMART

  

PROSITE

  

PRINTS