| Tag | Content |
|---|
| CPLM ID | CPLM-027931 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alpha-1 tubulin |
Protein Synonyms/Alias | Alpha-2 tubulin; Alpha-2-tubulin |
Gene Name | |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Giardia intestinalis (Giardia lamblia) |
NCBI Taxa ID | 5741 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 40 | DGQMPSDKTIGGGDD | acetylation | [1] |
|
Reference | [1] Posttranslational modifications of alpha- and beta-tubulin in Giardia lamblia, an ancient eukaryote. Weber K, Schneider A, Westermann S, Müller N, Plessmann U. FEBS Lett. 1997 Dec 8;419(1):87-91. [ PMID: 9426225] |
Functional Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). |
Sequence Annotation | |
Keyword | Cytoplasm; Cytoskeleton; GTP-binding; Microtubule; Nucleotide-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 454 AA |
Protein Sequence | MRECISVHIG QAGVQIGNAC WELYCLEHGI QHDGQMPSDK TIGGGDDAFN TFFSETGAGK 60
HVPRAVFVDL EPTVVDEVRA GSYRQLYHPE QLISGKEDAA NNYARGHYTI GKEIVDLVLD 120
RVRKLADNCS GLQGFLIFHS FGGGTGAGFG SLFLERLSVD YGRKSKLEFV VYPSPQIATA 180
VVEPYNTILA AHSMLEHSDC AFMVDNEAMY DICRRNLDIE RPTYTNLNRL IAQCISSITA 240
SLRFDGALNV DLTEFQTNLV PYPRIHFPLC SYAPIISSEK AYHEKLSVAE LTNSVFEPAN 300
MMVKCDPRHG KYMACCMMYR GDVVPKDVNA AIAVIKTKRT IQFVDWCPTG FKVGINYQPP 360
TVIPGGDLAK VQRSCLMISN TTAIAEVWSR MDHKFDLMYA KRAFVHWYVG EGMEEGEFSE 420
AREDLAALEK DYEEIGAETL GDGEGEDMEE DDAY 454 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro. GO:0007017; P:microtubule-based process; IEA:InterPro. GO:0051258; P:protein polymerization; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |