| Tag | Content |
|---|
| CPLM ID | CPLM-019510 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 |
Protein Synonyms/Alias | Centaurin-beta-5; Cnt-b5 |
Gene Name | ACAP3 |
Gene Synonyms/Alias | CENTB5; KIAA1716 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 10 | VEFEECVKDSPRFRA | ubiquitination | [1] | | 48 | SGMVEAGKAYVSTSR | ubiquitination | [1] | | 233 | VIDSAVEKREMERKH | ubiquitination | [1] | | 401 | DTRERGVKGESVLQR | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | GTPase-activating protein for the ADP ribosylation factor family (Potential). |
Sequence Annotation | DOMAIN 268 363 PH.
DOMAIN 403 525 Arf-GAP.
REPEAT 702 731 ANK 1.
REPEAT 735 764 ANK 2.
REPEAT 768 797 ANK 3.
ZN_FING 418 441 C4-type. |
Keyword | Alternative splicing; ANK repeat; Complete proteome; GTPase activation; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 834 AA |
Protein Sequence | MTVEFEECVK DSPRFRATID EVETDVVEIE AKLDKLVKLC SGMVEAGKAY VSTSRLFVSG 60
VRDLSQQCQG DTVISECLQR FADSLQEVVN YHMILFDQAQ RSVRQQLQSF VKEDVRKFKE 120
TKKQFDKVRE DLELSLVRNA QAPRHRPHEV EEATGALTLT RKCFRHLALD YVLQINVLQA 180
KKKFEILDSM LSFMHAQSSF FQQGYSLLHQ LDPYMKKLAA ELDQLVIDSA VEKREMERKH 240
AAIQQRTLLQ DFSYDESKVE FDVDAPSGVV MEGYLFKRAS NAFKTWNRRW FSIQNSQLVY 300
QKKLKDALTV VVDDLRLCSV KPCEDIERRF CFEVLSPTKS CMLQADSEKL RQAWVQAVQA 360
SIASAYRESP DSCYSERLDR TASPSTSSID SATDTRERGV KGESVLQRVQ SVAGNSQCGD 420
CGQPDPRWAS INLGVLLCIE CSGIHRSLGV HCSKVRSLTL DSWEPELLKL MCELGNSAVN 480
QIYEAQCEGA GSRKPTASSS RQDKEAWIKD KYVEKKFLRK APMAPALEAP RRWRVQKCLR 540
PHSSPRAPTA RRKVRLEPVL PCVAALSSVG TLDRKFRRDS LFCPDELDSL FSYFDAGAAG 600
AGPRSLSSDS GLGGSSDGSS DVLAFGSGSV VDSVTEEEGA ESEESSGEAD GDTEAEAWGL 660
ADVRELHPGL LAHRAARARD LPALAAALAH GAEVNWADAE DEGKTPLVQA VLGGSLIVCE 720
FLLQNGADVN QRDSRGRAPL HHATLLGRTG QVCLFLKRGA DQHALDQEQR DPLAIAVQAA 780
NADIVTLLRL ARMAEEMREA EAAPGPPGAL AGSPTELQFR RCIQEFISLH LEES 834 |
Gene Ontology | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro. GO:0005543; F:phospholipid binding; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0043547; P:positive regulation of GTPase activity; IEA:GOC. GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |