CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043255
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 F-box/LRR-repeat protein 19 
Protein Synonyms/Alias
  
Gene Name
 FBXL19 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
334RMDLSRRKSLTPPMLubiquitination[1]
410LRWIEDVKDSQLRELubiquitination[1]
425LLPPPDTKPGQTESRubiquitination[1]
552PFRCPEEKLLLKDS*ubiquitination[1]
556PEEKLLLKDS*****ubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 558 AA 
Protein Sequence
MSSSSRGPGA GARRRRTRCR RCRACVRTEC GDCHFCRDMK KFGGPGRMKQ SCLLRQCTAP 60
VLPHTAVCLL CGEAGKEDTV EGEEEKFGLS LMECTICNEI VHPGCLKMGK AEGVINAEIP 120
NCWECPRCTQ EGRTSKVKGG RERHLKKKPK PPLASAEGPA VPSPSPQREK LERFKRMCQL 180
LERVPDTSSS SSDSDSDSDS SGTSLSEDEA PGEARNGRRP ARGSSGEKEN RGGRRAVRPG 240
SGGPLLSWPL GPAPPPRPPQ LERHVVRPPP RSPEPDTLPL AAGSDHPLPR AAWLRVFQHL 300
GPRELCICMR VCRTWSRWCY DKRLWPRMDL SRRKSLTPPM LSGVVRRQPR ALDLSWTGVS 360
KKQLMWLLNR LQGLQELVLS GCSWLSVSAL GSAPLPALRL LDLRWIEDVK DSQLRELLLP 420
PPDTKPGQTE SRGRLQGVAE LRLAGLELTD ASLRLLLRHA PQLSALDLSH CAHVGDPSVH 480
LLTAPTSPLR ETLVHLNLAG CHRLTDHCLP LFRRCPRLRR LDLRSCRQLS PEACARLAAA 540
GPPGPFRCPE EKLLLKDS 558 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001810; F-box_dom_cyclin-like.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR002857; Znf_CXXC.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF00646; F-box
 PF02008; zf-CXXC 
SMART
 SM00256; FBOX
 SM00249; PHD 
PROSITE
 PS51058; ZF_CXXC
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS