CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033419
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synemin 
Protein Synonyms/Alias
  
Gene Name
 SYNM 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
339MPSEFRNKSYHYTDSubiquitination[1]
416QQENSYGKAVSSQTNubiquitination[1]
1233RSVISDEKKVALLYLubiquitination[2]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Intermediate filament; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1252 AA 
Protein Sequence
MLSWRLQTGP EKAELQELNA RLYDYVCRVR ELERENLLLE EELRGRRGRE GLWAEGQARC 60
AEEARSLRQQ LDELSWATAL AEGERDALRR ELRELQRLDA EERAARGRLD AELGAQQREL 120
QEALGARAAL EALLGRLQAE RRGLDAAHER DVRELRARAA SLTMHFRARA TGPAAPPPRL 180
REVHDSYALL VAESWRETVQ LYEDEVRELE EALRRGQESR LQAEEETRLC AQEAALRREA 240
LGLEQLRARL EDALLRMREE YGIQAEERQR VIDCLEDEKA TLTLAMADWL RDYQDLLQVK 300
TGLSLEVATY RALLEGESNP EIVIWAEHVE NMPSEFRNKS YHYTDSLLQR ENERNLFSRQ 360
KAPLASFNHS SALYSNLSGH RGSQTGTSIG GDARRGFLGS GYSSSATTQQ ENSYGKAVSS 420
QTNVRTFSPT YGLLRNTEAQ VKTFPDRPKA GDTREVPVYI GEDSTIARES YRDRRDKVAA 480
GASESTRSNE RTVILGKKTE VKATREQERN RPETIRTKPE EKMFDSKEKA SEERNLRWEE 540
LTKLDKEARQ RESQQMKEKA KEKDSPKEKS VREREVPISL EVSQDRRAEV SPKGLQTPVK 600
DAGGGTGREA EARELRFRLG TSDATGSLQG DSMTETVAEN IVTSILKQFT QSPETEASAD 660
SFPDTKVTYV DRKELPGERK TKTEIVVESK LTEDVDVSDE AGLDYLLSKD IKEVGLKGKS 720
AEQMIGDIIN LGLKGREGRA KVVNVEIVEE PVSYVSGEKP EEFSVPFKVE EVEDVSPGPW 780
GLVKEEEGYG ESDVTFSVNQ HRRTKQPQEN TTHVEEVTEA GDSEGEQSYF VSTPDEHPGG 840
HDRDDGSVYG QIHIEEESTI RYSWQDEIVQ GTRRRTQKDG AVGEKVVKPL DVPAPSLEGD 900
LGSTHWKEQA RSGEFHAEPT VIEKEIKIPH EFHTSMKGIS SKEPRQQLVE VIGQLEETLP 960
ERMREELSAL TREGQGGPGS VSVDVKKVQG AGGSSVTLVA EVNVSQTVDA DRLDLEELSK 1020
DEASEMEKAV ESVVRESLSR QRSPAPGSPD EEGGAEAPAA GIRFRRWATR ELYIPSGESE 1080
VAGGASHSSG QRTPQGPVSA TVEVSSPTGF AQSQVLEDVS QAARHIKLGP SEVWRTERMS 1140
YEGPTAEVVE MDVSNVEAIR SRTQEAGALG VSDRGSWRDA DSRNDQAVGV SFKASAGEGD 1200
QAHREQGKEQ AMFDKKVQLQ RMVDQRSVIS DEKKVALLYL DNEEEENDGH WF 1252 
Gene Ontology
 GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
 GO:0005198; F:structural molecule activity; IEA:InterPro. 
Interpro
 IPR016044; F.
 IPR001664; IF.
 IPR018039; Intermediate_filament_CS. 
Pfam
 PF00038; Filament 
SMART
  
PROSITE
 PS00226; IF 
PRINTS