CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030371
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 EG620155 protein 
Protein Synonyms/Alias
 Uncharacterized protein 
Gene Name
 Gm6133 
Gene Synonyms/Alias
 EG620155 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
46MNIHKATKYLKDVTLacetylation[1]
49HKATKYLKDVTLKKQacetylation[1, 2]
49HKATKYLKDVTLKKQubiquitination[3]
55LKDVTLKKQCVPFRRacetylation[2]
55LKDVTLKKQCVPFRRubiquitination[3]
159EKEQIVPKPEEEVAQacetylation[1, 4, 5]
177ITQKKLGKKKNSWHRacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [4] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [5] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 190 AA 
Protein Sequence
MVPYSFDPEA PTKSCKSRGS NFCVHSKNTW ETAQAIKGMN IHKATKYLKD VTLKKQCVPF 60
RRYHGGVGTC TQAKHWGWIQ GRWPEMSAEF LLHMLENAES NAELKSLDVD SLVIEHIQVN 120
KAPKMRRRTY RAHGPINPYM SSPCHIEMIL TEKEQIVPKP EEEVAQKKKI TQKKLGKKKN 180
SWHRNKFSIK 190 
Gene Ontology
 GO:0015934; C:large ribosomal subunit; IEA:InterPro.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR001063; Ribosomal_L22.
 IPR005721; Ribosomal_L22/L17_euk/arc. 
Pfam
 PF00237; Ribosomal_L22 
SMART
  
PROSITE
  
PRINTS