| Tag | Content |
|---|
| CPLM ID | CPLM-021597 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pleckstrin homology domain-containing family A member 3 |
Protein Synonyms/Alias | PH domain-containing family A member 3; Phosphatidylinositol-four-phosphate adapter protein 1; FAPP-1; Phosphoinositol 4-phosphate adapter protein 1 |
Gene Name | PLEKHA3 |
Gene Synonyms/Alias | FAPP1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 92 | LVALGSSKACLTDTR | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4-phosphate (PtdIns4P). |
Sequence Annotation | DOMAIN 1 93 PH. |
Keyword | 3D-structure; Complete proteome; Golgi apparatus; Lipid-binding; Membrane; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 300 AA |
Protein Sequence | MEGVLYKWTN YLTGWQPRWF VLDNGILSYY DSQDDVCKGS KGSIKMAVCE IKVHSADNTR 60
MELIIPGEQH FYMKAVNAAE RQRWLVALGS SKACLTDTRT KKEKEISETS ESLKTKMSEL 120
RLYCDLLMQQ VHTIQEFVHH DENHSSPSAE NMNEASSLLS ATCNTFITTL EECVKIANAK 180
FKPEMFQLHH PDPLVSPVSP SPVQMMKRSV SHPGSCSSER SSHSIKEPVS TLHRLSQRRR 240
RTYSDTDSCS DIPLEDPDRP VHCSKNTLNG DLASATIPEE SRLMAKKQSE SEDTLPSFSS 300 |
Gene Ontology | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. GO:0016020; C:membrane; IEA:UniProtKB-KW. GO:0005545; F:1-phosphatidylinositol binding; IEA:Compara. GO:0005543; F:phospholipid binding; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |