CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015109
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc transporter 6 
Protein Synonyms/Alias
 ZnT-6; Solute carrier family 30 member 6 
Gene Name
 SLC30A6 
Gene Synonyms/Alias
 ZNT6 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
17PQRSFFGKLLREFRLubiquitination[1]
268HVIGQLDKLIREVSTubiquitination[1, 2]
379PVTSTPAKPSSPPPEubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
 Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Golgi apparatus; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 461 AA 
Protein Sequence
MGTIHLFRKP QRSFFGKLLR EFRLVAADRR SWKILLFGVI NLICTGFLLM WCSSTNSIAL 60
TAYTYLTIFD LFSLMTCLIS YWVTLRKPSP VYSFGFERLE VLAVFASTVL AQLGALFILK 120
ESAERFLEQP EIHTGRLLVG TFVALCFNLF TMLSIRNKPF AYVSEAASTS WLQEHVADLS 180
RSLCGIIPGL SSIFLPRMNP FVLIDLAGAF ALCITYMLIE INNYFAVDTA SAIAIALMTF 240
GTMYPMSVYS GKVLLQTTPP HVIGQLDKLI REVSTLDGVL EVRNEHFWTL GFGSLAGSVH 300
VRIRRDANEQ MVLAHVTNRL YTLVSTLTVQ IFKDDWIRPA LLSGPVAANV LNFSDHHVIP 360
MPLLKGTDDL NPVTSTPAKP SSPPPEFSFN TPGKNVNPVI LLNTQTRPYG FGLNHGHTPY 420
SSMLNQGLGV PGIGATQGLR TGFTNIPSRY GTNNRIGQPR P 461 
Gene Ontology
 GO:0000139; C:Golgi membrane; TAS:Reactome.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005385; F:zinc ion transmembrane transporter activity; IEA:Compara.
 GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
 GO:0006895; P:Golgi to endosome transport; IEA:Compara.
 GO:0055085; P:transmembrane transport; TAS:Reactome. 
Interpro
 IPR002524; Cation_efflux.
 IPR027469; Cation_efflux_TMD. 
Pfam
 PF01545; Cation_efflux 
SMART
  
PROSITE
  
PRINTS