| Tag | Content |
|---|
| CPLM ID | CPLM-012096 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc transporter ZIP6 |
Protein Synonyms/Alias | Estrogen-regulated protein LIV-1; Solute carrier family 39 member 6; Zrt- and Irt-like protein 6; ZIP-6 |
Gene Name | SLC39A6 |
Gene Synonyms/Alias | LIV1; ZIP6 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 182 | KKKKNQKKPENDDDV | ubiquitination | [1] | | 192 | NDDDVEIKKQLSKYE | ubiquitination | [1] | | 197 | EIKKQLSKYESQLST | ubiquitination | [1] | | 208 | QLSTNEEKVDTDDRT | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | May act as a zinc-influx transporter. |
Sequence Annotation | CARBOHYD 67 67 N-linked (GlcNAc...).
CARBOHYD 68 68 N-linked (GlcNAc...); atypical.
CARBOHYD 241 241 N-linked (GlcNAc...).
CARBOHYD 266 266 N-linked (GlcNAc...) (Potential).
CARBOHYD 283 283 N-linked (GlcNAc...) (Potential).
CARBOHYD 684 684 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Cell membrane; Coiled coil; Complete proteome; Direct protein sequencing; Glycoprotein; Ion transport; Membrane; Polymorphism; Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 755 AA |
Protein Sequence | MGIQVPLNAT EFNYLCPAII NQIDARSCLI HTSEKKAEIP PKTYSLQIAW VGGFIAISII 60
SFLSLLGVIL VPLMNRVFFK FLLSFLVALA VGTLSGDAFL HLLPHSHASH HHSHSHEEPA 120
MEMKRGPLFS HLSSQNIEES AYFDSTWKGL TALGGLYFMF LVEHVLTLIK QFKDKKKKNQ 180
KKPENDDDVE IKKQLSKYES QLSTNEEKVD TDDRTEGYLR ADSQEPSHFD SQQPAVLEEE 240
EVMIAHAHPQ EVYNEYVPRG CKNKCHSHFH DTLGQSDDLI HHHHDYHHIL HHHHHQNHHP 300
HSHSQRYSRE ELKDAGVATL AWMVIMGDGL HNFSDGLAIG AAFTEGLSSG LSTSVAVFCH 360
ELPHELGDFA VLLKAGMTVK QAVLYNALSA MLAYLGMATG IFIGHYAENV SMWIFALTAG 420
LFMYVALVDM VSF 433 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IEA:Compara. GO:0005887; C:integral to plasma membrane; IDA:BHF-UCL. GO:0031258; C:lamellipodium membrane; IDA:UniProtKB. GO:0005385; F:zinc ion transmembrane transporter activity; IDA:BHF-UCL. GO:0006882; P:cellular zinc ion homeostasis; IDA:BHF-UCL. GO:0071578; P:zinc ion transmembrane import; IDA:BHF-UCL. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |