UniProt Accession

 VAMP3_RAT; P63025; Q64271 

Genbank Protein ID

 S63830; BC088119 

Genbank Nucleotide ID

 AAB27554.1; AAH88119.1 

Protein Name

 Vesicle-associated membrane protein 3 

Protein Synonyms/Alias

 VAMP-3; Cellubrevin; CEB; Synaptobrevin-3 

Gene Name

 Vamp3 

Gene Synonyms/Alias

 Syb3 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
39	IMRVNVDKVLERDQK	ubiquitination	[1]
46	KVLERDQKLSELDDR	acetylation	[2]
46	KVLERDQKLSELDDR	ubiquitination	[1]
70	QFETSAAKLKRKYWW	ubiquitination	[1]
72	ETSAAKLKRKYWWKN	ubiquitination	[1]

Reference

 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network (By similarity). 

Sequence Annotation

 DOMAIN 18 78 v-SNARE coiled-coil homology.
 MOD_RES 48 48 Phosphoserine (By similarity).  

Keyword

 Cell junction; Coiled coil; Complete proteome; Membrane; Phosphoprotein; Protein transport; Reference proteome; Synapse; Synaptosome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 103 AA 

Protein Sequence

Gene Ontology

 GO:0016324; C:apical plasma membrane; IDA:RGD.
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0030665; C:clathrin-coated vesicle membrane; IDA:RGD.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell.
 GO:0055037; C:recycling endosome; IDA:RGD.
 GO:0030141; C:secretory granule; IEA:Compara.
 GO:0031201; C:SNARE complex; IDA:RGD.
 GO:0045202; C:synapse; IEA:UniProtKB-KW.
 GO:0017156; P:calcium ion-dependent exocytosis; IEA:Compara.
 GO:0043001; P:Golgi to plasma membrane protein transport; IEA:Compara.
 GO:0001921; P:positive regulation of receptor recycling; ISS:UniProtKB.
 GO:0006461; P:protein complex assembly; IDA:RGD.
 GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
 GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB. 

Interpro

 IPR001388; Synaptobrevin.
 IPR016444; Synaptobrevin_met/fun. 

Pfam

 PF00957; Synaptobrevin 

SMART

  

PROSITE

 PS00417; SYNAPTOBREVIN
 PS50892; V_SNARE 

PRINTS

 PR00219; SYNAPTOBREVN.