UniProt Accession

 D3YW66_MOUSE; D3YW66 

Genbank Protein ID

 AC120402 

Genbank Nucleotide ID

  

Protein Name

 Ubiquinone biosynthesis monooxygenase COQ6 

Protein Synonyms/Alias

  

Gene Name

 Coq6 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
172	EAVADRVKVLYESKA	acetylation	[1]
219	LIGADGHKSGVRQAA	acetylation	[1, 2, 3]
219	LIGADGHKSGVRQAA	succinylation	[3]

Reference

 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 432 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
 GO:0006744; P:ubiquinone biosynthetic process; IEA:InterPro. 

Interpro

 IPR002938; mOase_FAD-bd.
 IPR003042; Rng_hydrolase-like.
 IPR018168; Ubi_Hdrlase_CS.
 IPR010971; Ubi_Hdrxlases.
 IPR000689; UbQ_biosynth_mOase. 

Pfam

 PF01494; FAD_binding_3 

SMART

  

PROSITE

 PS01304; UBIH 

PRINTS

 PR00420; RNGMNOXGNASE.