| Tag | Content |
|---|
| CPLM ID | CPLM-007316 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Carboxypeptidase Y-deficient protein 8 |
Protein Synonyms/Alias | Vacuolar protein sorting-associated protein 26; Vacuolar protein-targeting protein 4 |
Gene Name | PEP8 |
Gene Synonyms/Alias | GRD6; VPS26; VPT4; YJL053W; J1152 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 93 | SGNSSSKKVTSSTSS | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor VPS10. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The VPS29-VPS26-VPS35 subcomplex may be involved in cargo selection. |
Sequence Annotation | MOD_RES 216 216 Phosphoserine. |
Keyword | Complete proteome; Phosphoprotein; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 379 AA |
Protein Sequence | MSIFFKPPID IEILFDNEES RKHVDIATRS SNSSYKSMKE SLPVYEDGES LGGIVTLRVR 60
DSKKVDHLGI KVSVIGSIDM LKSHGSGNSS SKKVTSSTSS SSSNGSVDVR KNSVDQFLCQ 120
SYDLCPAGEL QHSQSFPFLF RDLSKRYESY KGKNVDVAYY VKVTVMRKST DISKIKRFWV 180
YLYNSVTTAP NTLSANETKA TTNDIAGGNY AADNASDNTQ TKSTQGEAAD VNQVLPISHS 240
NNEPKPVRLD IGIENCLHIE FEYAKSQYSL KEVIVGRIYF LLTRLRIKHM ELSLITRESS 300
GLQTSNVMTD STAIRYEIMD GSSVKGETIP IRLFLSGYDL TPNMSCNYFN VKNYLSLVII 360
DEDGRRYFKQ SEITLYRTR 379 |
Gene Ontology | GO:0005768; C:endosome; IPI:SGD. GO:0000329; C:fungal-type vacuole membrane; IDA:SGD. GO:0030906; C:retromer complex, inner shell; IMP:SGD. GO:0045053; P:protein retention in Golgi apparatus; IMP:SGD. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0042147; P:retrograde transport, endosome to Golgi; IPI:SGD. GO:0007034; P:vacuolar transport; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |