UniProt Accession

 ENO_MYCPN; P75189; Q50324 

Genbank Protein ID

 U00089; U43738 

Genbank Nucleotide ID

 AAB95884.1; AAC43651.1 

Protein Name

 Enolase 

Protein Synonyms/Alias

 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase 

Gene Name

 eno 

Gene Synonyms/Alias

 MPN_606; MP236 

Created Date

 July 27, 2013 

Organism

 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 

NCBI Taxa ID

 272634 

Lysine Modification

Position	Peptide	Type	References
54	SGASTGEKEAIELRD	acetylation	[1]
70	DPKAYFGKGVSQAVQ	acetylation	[1]
140	AQKTSLFKYLANQVM	acetylation	[1]
205	ETFHALQKLLKQRGL	acetylation	[1]
362	ATNSILIKLNQIGTL	acetylation	[1]
425	SRSERIAKYNRLLQI	acetylation	[1]

Reference

 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 

Functional Description

 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). 

Sequence Annotation

 REGION 389 392 Substrate binding (By similarity).
 ACT_SITE 219 219 Proton donor (By similarity).
 ACT_SITE 362 362 Proton acceptor (By similarity).
 METAL 256 256 Magnesium (By similarity).
 METAL 310 310 Magnesium (By similarity).
 METAL 337 337 Magnesium (By similarity).
 BINDING 169 169 Substrate (By similarity).
 BINDING 178 178 Substrate (By similarity).
 BINDING 310 310 Substrate (By similarity).
 BINDING 337 337 Substrate (By similarity).
 BINDING 362 362 Substrate (covalent); in inhibited form
 BINDING 413 413 Substrate (By similarity).
 MOD_RES 304 304 Phosphotyrosine (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Glycolysis; Lyase; Magnesium; Metal-binding; Phosphoprotein; Reference proteome; Secreted. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 456 AA 

Protein Sequence

Gene Ontology

 GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0004634; F:phosphopyruvate hydratase activity; IEA:HAMAP.
 GO:0006096; P:glycolysis; IEA:HAMAP. 

Interpro

 IPR000941; Enolase.
 IPR020810; Enolase_C.
 IPR020809; Enolase_CS.
 IPR020811; Enolase_N. 

Pfam

 PF00113; Enolase_C
 PF03952; Enolase_N 

SMART

  

PROSITE

 PS00164; ENOLASE 

PRINTS

 PR00148; ENOLASE.