CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008959
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Membrane-associated protein Hem 
Protein Synonyms/Alias
 dHem-2 
Gene Name
 Hem 
Gene Synonyms/Alias
 HEM2; CG5837 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
395PLLKNKGKSNEDLVDacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Plays a role during growth of the oocyte. 
Sequence Annotation
  
Keyword
 Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1126 AA 
Protein Sequence
MARPIFPNQQ KIAEKLIILN DRGLGILTRI YNIKKACGDT KSKPGFLSEK SLESSIKFIV 60
KRFPNIDVKG LNAIVNIKAE IIKSLSLYYH TFVDLLDFKD NVCELLTTMD ACQIHLDITL 120
NFELTKYYLD LVVTYVSLMI VLSRVEDRKA VLGLYNAAYE LQNNQADTGF PRLGQMILDY 180
EVPLKKLAEE FIPHQRLLTS ALRSLTSIYA LRNLPADKWR EMQKLSLVGN PAILLKAVRT 240
DTMSCEYISL EAMDRWIIFG LLLNHQMLGQ YPEVNKIWLS ALESSWVVAL FRDEVLQIHQ 300
YIQATFDGIK GYSKRIGEVK EAYNTAVQKA ALMHRERRKF LRTALKELAL IMTDQPGLLG 360
PKAIFIFIGL CLARDEILWL LRHNDNPPLL KNKGKSNEDL VDRQLPELLF HMEELRALVR 420
KYSQVMQRYY VQYLSGFDAT DLNIRMQSLQ MCPEDESIIF SSLYNTAAAL TVKQVEDNEL 480
FYFRPFRLDW FRLQTYMSVG KAALRIAEHA ELARLLDSMV FHTRVVDNLD EILVETSDLS 540
IFCFYNKMFD DQFHMCLEFP AQNRYIIAFP LICSHFQNCT HEMCPEERHH IRERSLSVVN 600
IFLEEMAKEA KNIITTICDE QCTMADALLP KHCAKILSVQ SARKKKDKSK SKHFDDIRKP 660
GDESYRKTRE DLTTMDKLHM ALTELCFAIN YCPTVNVWEF AFAPREYLCQ NLEHRFSRDL 720
VGMVMFNQET MEIAKPSELL ASVRAYMNVL QTVENYVHID ITRVFNNCLL QQTQALDSHG 780
EKTIAALYNT WYSEVLLRRV SAGNIVFSIN QKAFVPISPE GWVPFNPQEF SDLNELRALA 840
ELVGPYGIKT LNETLMWHIA NQVQELKSLV STNKEVLITL RTSFDKPEVM KEQFKRLQDV 900
DRVLQRMTII GVIICFRNLV HEALVDVLDK RIPFLLSSVK DFQEHLPGGD QIRVASEMAS 960
AAGLLCKVDP TLATTLKSKK PEFDEGEHLT ACLLMVFVAV SIPKLARNEN SFYRATIDGH 1020
SNNTHCMAAA INNIFGALFT ICGQSDMEDR MKEFLALASS SLLRLGQESD KEATRNRESI 1080
YLLLDEIVKQ SPFLTMDLLE SCFPYVLIRN AYHGVYKQEQ ILGLAL 1126 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IDA:FlyBase.
 GO:0031209; C:SCAR complex; IPI:FlyBase.
 GO:0007409; P:axonogenesis; IMP:FlyBase.
 GO:0030031; P:cell projection assembly; IMP:FlyBase.
 GO:0007417; P:central nervous system development; IMP:FlyBase.
 GO:0008407; P:chaeta morphogenesis; IMP:FlyBase.
 GO:0030866; P:cortical actin cytoskeleton organization; IMP:FlyBase.
 GO:0007520; P:myoblast fusion; IMP:FlyBase.
 GO:0007528; P:neuromuscular junction development; IMP:FlyBase.
 GO:0001764; P:neuron migration; IMP:FlyBase.
 GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.
 GO:0008360; P:regulation of cell shape; IMP:FlyBase. 
Interpro
 IPR019137; Nck-associated_protein-1. 
Pfam
 PF09735; Nckap1 
SMART
  
PROSITE
  
PRINTS