CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040299
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Calcium/calmodulin-dependent protein kinase type II subunit alpha 
Protein Synonyms/Alias
  
Gene Name
 Camk2a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
152ENLLLASKLKGAAVKubiquitination[1]
154LLLASKLKGAAVKLAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 177 AA 
Protein Sequence
XLCKGCSWLG DVAARVWTCI CVHMCGRGAF SVVRRCVKVL AGQEYAAKII NTKKLSARDH 60
QKLEREARIC RLLKHPNIVR LHDSISEEGH HYLIFDLVTG GELFEDIVAR EYYSEADASH 120
CIQQILEAVL HCHQMGVVHR DLKPENLLLA SKLKGAAVKL ADFGLAIEVE GEQQAWF 177 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
 GO:0006816; P:calcium ion transport; IMP:MGI.
 GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.
 GO:0046777; P:protein autophosphorylation; IMP:MGI.
 GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:MGI.
 GO:0046928; P:regulation of neurotransmitter secretion; IMP:MGI. 
Interpro
 IPR020636; Ca/CaM-dep_Ca-dep_prot_Kinase.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
  
PROSITE
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS