UniProt Accession

 TRI62_HUMAN; Q9BVG3; B3KVH5; D3DPR1; Q9NVG0 

Genbank Protein ID

 AK001621; AK122896; AL662907; CH471059; CH471059; BC001222; BC007999; BC011689; BC012152 

Genbank Nucleotide ID

 BAA91792.1; BAG53787.1; CAH70402.1; EAX07466.1; EAX07467.1; AAH01222.1; AAH07999.1; AAH11689.1; AAH12152.1 

Protein Name

 Tripartite motif-containing protein 62 

Protein Synonyms/Alias

  

Gene Name

 TRIM62 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
67	PALAPSLKLANIVER	ubiquitination	[1, 2, 3]
100	CQAHDKVKLFCLTDR	ubiquitination	[3]
161	TEALQLLKRQLAETK	ubiquitination	[1]
194	RLLRERQKAMLEELE	ubiquitination	[3]
214	TLTDIEQKVQRYSQQ	ubiquitination	[1, 3]
224	RYSQQLRKVQEGAQI	ubiquitination	[3]
258	LSERLKGKIHETNLT	ubiquitination	[1]
273	YEDFPTSKYTGPLQY	ubiquitination	[3]
375	AHEAASRKGSIQIQP	ubiquitination	[3]
463	GQSHANGKNVQPLRI	ubiquitination	[3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

 DOMAIN 277 475 B30.2/SPRY.
 ZN_FING 11 54 RING-type.
 ZN_FING 88 128 B box-type.  

Keyword

 Coiled coil; Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 475 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR001870; B30.2/SPRY.
 IPR003879; Butyrophylin.
 IPR008985; ConA-like_lec_gl_sf.
 IPR006574; PRY.
 IPR003877; SPRY_rcpt.
 IPR000315; Znf_B-box.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 

Pfam

 PF00622; SPRY
 PF00643; zf-B_box 

SMART

 SM00589; PRY
 SM00184; RING 

PROSITE

 PS50188; B302_SPRY
 PS50119; ZF_BBOX
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 

PRINTS

 PR01407; BUTYPHLNCDUF.