CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002261
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome c oxidase subunit 3 
Protein Synonyms/Alias
 Cytochrome c oxidase polypeptide III 
Gene Name
 Mtco3 
Gene Synonyms/Alias
 Coiii; mt-Co3 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
224VCLLRQLKFHFTSKHacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Subunits I, II and III form the functional core of the enzyme complex. 
Sequence Annotation
  
Keyword
 Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 261 AA 
Protein Sequence
MTHQTHAYHM VNPSPWPLTG ALSALLLTSG LVMWFHYNST ILLSLGLLTN ILTMYQWWRD 60
IIREGTYQGH HTPIVQKGLR YGMILFIVSE VFFFAGFFWA FYHSSLVPTH DLGGCWPPTG 120
ITPLNPLEVP LLNTSVLLAS GVSITWAHHS LMEGNRNHMN QALLITILLG LYFTILQASE 180
YFETSFSISD GIYGSTFFMA TGFHGLHVII GSTFLIVCLL RQLKFHFTSK HHFGFEAAAW 240
YWHFVDVVWL FLYVSIYWWG S 261 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
 GO:0019646; P:aerobic electron transport chain; IEA:InterPro. 
Interpro
 IPR024791; Cyt_c/ubiquinol_Oxase_su3.
 IPR000298; Cyt_c_oxidase_su3.
 IPR013833; Cyt_c_oxidase_su3_a-hlx. 
Pfam
 PF00510; COX3 
SMART
  
PROSITE
 PS50253; COX3 
PRINTS