CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024272
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ferritin BfrB 
Protein Synonyms/Alias
 Non-heme ferritin Ftn 
Gene Name
 bfrB 
Gene Synonyms/Alias
 ftn; MSMEG_6422; MSMEI_6254 
Created Date
 July 27, 2013 
Organism
 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
NCBI Taxa ID
 246196 
Lysine Modification
Position
Peptide
Type
References
10NSGALDTKFHALIQDpupylation[1]
Reference
 [1] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657
Functional Description
 Iron-storage protein that displays ferroxidase activity, catalyzing the oxidation of Fe(2+) ions into Fe(3+) ions, that can then be deposited as a ferric-oxide mineral core within the central cavity of the protein complex (By similarity). 
Sequence Annotation
 DOMAIN 5 150 Ferritin-like diiron.
 METAL 22 22 Iron 1 (By similarity).
 METAL 55 55 Iron 1 (By similarity).
 METAL 55 55 Iron 2 (By similarity).
 METAL 58 58 Iron 1 (By similarity).
 METAL 99 99 Iron 2 (By similarity).
 METAL 132 132 Iron 2 (By similarity).
 CROSSLNK 10 10 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; Iron; Iron storage; Isopeptide bond; Metal-binding; Oxidoreductase; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 181 AA 
Protein Sequence
MTNSGALDTK FHALIQDQIR SEFTASQQYI AIAVFFDGAD LPQLAKHFYA QALEERNHAM 60
MLVQYLLDRD VEVEIPGIDP VCNNFTTPRD ALALALDQER TVTEQISRLA SVARDEGDHL 120
GEQFMQWFLK EQVEEVAAMT TLVRIADRAG SNLFHIEDFV AREMSAAGAD PTAPRAAGGA 180
L 181 
Gene Ontology
 GO:0008199; F:ferric iron binding; IEA:InterPro.
 GO:0004322; F:ferroxidase activity; IEA:EC.
 GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.
 GO:0006826; P:iron ion transport; IEA:InterPro. 
Interpro
 IPR001519; Ferritin.
 IPR009040; Ferritin-like_diiron.
 IPR009078; Ferritin-like_SF.
 IPR012347; Ferritin-rel.
 IPR008331; Ferritin_DPS_dom. 
Pfam
 PF00210; Ferritin 
SMART
  
PROSITE
 PS50905; FERRITIN_LIKE 
PRINTS