CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029184
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Mediator of RNA polymerase II transcription subunit 24 
Protein Synonyms/Alias
  
Gene Name
 Med24 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
439PTVTNILKTMDADHSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1006 AA 
Protein Sequence
MKVVNLKQAI LQAWKERWSD YQWAINMKKF FPKGATWDIL NLAEALLEQA MIGPSPNPLI 60
LSYLKYAISS QMVSCSSVLT AISKFDDFSR DLCVQALLDI MDMFCDRLSC HGKAEECIGL 120
CRALLSALHW LLRCTAASAE RLQEGLEAGT PAPGEKQLAL CLQCLEKTLS STKNRALLHI 180
AKLEEASLHT SQGLGQGGTR ANQPTASWTA IEHSLLKLGE ILANLSNPQL RSQAERCGTL 240
IRSIPSMLSV HSEQLHKTGF PTIHALILLE GTMNLTGEMQ PLVEQLMMVK RMQHIPTPLF 300
VLEIWKACFV GLIESPEGTQ ELKWTAFTYL KIPQVLVKLK KYFHGEKDFT EDVNCAFEFL 360
LKLTPLLDKA DQRCNCDCTN FLLQECNKQG LLSEVNFASL VGKRTADRDP QLKSSENANI 420
QPNPGLILRA EPTVTNILKT MDADHSKSPE GLLGVLGHML SGKSLDLLLA AAAATGKLKS 480
FARKFINLNE FTTHGSGEST KTASVRALLF DISFLMLCHV AQTYGSEVIL SESSSGEEVP 540
FFETWMQTCM PEEGKILNPD HPCFRPDSTK VESLVALLNN SSEMKLVQMK WHEACLSISA 600
AILEILNAWE NGVLAFESIQ KITDNIKGKV CSLAVCAVAW LVAHVRMLGL DEREKSLQMI 660
RQLAGPLYSE NTLQFYNERV VIMNSILEHM CADVLQQTAT QIKFPSTGVD TMPYWNLLPP 720
KRPIKEVLTD IFAKVLEKGW VDSRSIHILD TLLHMGGVYW FCNNLIKELL KETRKEHTLR 780
AVQLLYSIFC LDMQQVTLVL LGHILPGLLT DSSKWHSLMD PPGTALAKLA VWCALSSYSS 840
HKGQASSRQK KRHREDIEDY VSLFPVEDMQ PSKLMRLLSS SDDDANILSS PTDRSMNSSL 900
SASQLHTVNM RDPLNRVLAN LFLLISSILG SRTAGPHTQF VQWFMEECVG CLEQDSRGSI 960
LQFMPFTTVS ELVKVSAMSS PKVVLAITDL SLPLGRQVAA KAIAAL 1006 
Gene Ontology
 GO:0016592; C:mediator complex; IDA:MGI.
 GO:0019827; P:stem cell maintenance; IMP:MGI.
 GO:0006366; P:transcription from RNA polymerase II promoter; IMP:MGI. 
Interpro
 IPR021429; Mediator_Med24_N. 
Pfam
 PF11277; Med24_N 
SMART
  
PROSITE
  
PRINTS