CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011867
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable electron transfer flavoprotein subunit alpha, mitochondrial 
Protein Synonyms/Alias
 Alpha-ETF; Altered inheritance rate of mitochondria protein 45 
Gene Name
 AIM45 
Gene Synonyms/Alias
 YPR004C; LPZ4C; YP9723.04C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
215WVKTILTKSERPELTacetylation[1]
339IVPELTEKLGKYK**acetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl- CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). 
Sequence Annotation
 NP_BIND 284 312 FAD (Potential).  
Keyword
 Complete proteome; Electron transport; FAD; Flavoprotein; Mitochondrion; Reference proteome; Transit peptide; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 344 AA 
Protein Sequence
MFKSLAAVLP RASKAKFLQK NYASTLAFIE SSKDGSVSRS SLSLLAAAQK LSNPITAVIT 60
GSKAEKTAEA LKSSYSCSNL EKLVIFEDSK LDTCLPEQLT PLLVKLLKGG DYSHFVVSNS 120
SVGKSVLPRV GALLDVQPVC EVTVIKDPKT FIRPIYAGNI ISTIECQAEK KLLIIRASAF 180
PPIAEGSMDS VTIEKRTDIP PCDLNVTWVK TILTKSERPE LTSAQNVVTG GRALKDKETF 240
EKLLSPLADV LHAAIGATRA SVDNGLCDNS LQIGQTGKVV APNLYIAIGV SGAVQHLAGM 300
KDSKVIVAIN NDPDAPIFNV ADYGLQGDLY KIVPELTEKL GKYK 344 
Gene Ontology
 GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. 
Interpro
 IPR001308; ETF_a.
 IPR014730; ETF_a/b_N.
 IPR014731; ETF_asu_C.
 IPR018206; ETF_asu_C_CS.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF01012; ETF
 PF00766; ETF_alpha 
SMART
 SM00893; ETF 
PROSITE
 PS00696; ETF_ALPHA 
PRINTS