UniProt Accession

 UFM1_HUMAN; P61960; Q14346; Q5VXS0; Q6IAG6; Q9CPX2; Q9NZF2 

Genbank Protein ID

 AB154404; AF208844; CR457189; DA664581; AL356863; AL356863; BC005193; Z70222 

Genbank Nucleotide ID

 BAD15373.1; AAF64258.1; CAG33470.1; CAH70411.1; CAH70414.1; AAH05193.1; CAA94181.1 

Protein Name

 Ubiquitin-fold modifier 1 

Protein Synonyms/Alias

  

Gene Name

 UFM1 

Gene Synonyms/Alias

 C13orf20; BM-002 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
19	SDPRLPYKVLSVPES	ubiquitination	[1, 2, 3]
69	TAGNVFLKHGSELRI	acetylation	[4]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [4] Monoclonal antibody cocktail as an enrichment tool for acetylome analysis.
 Shaw PG, Chaerkady R, Zhang Z, Davidson NE, Pandey A.
 Anal Chem. 2011 May 15;83(10):3623-6. [PMID: 21466224] 

Functional Description

 Ubiquitin-like modifier protein which binds to a number of target proteins, such as DDRGK1. 

Sequence Annotation

 CROSSLNK 83 83 Glycyl lysine isopeptide (Gly-Lys)  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Isopeptide bond; Nucleus; Reference proteome; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 85 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0071569; P:protein ufmylation; IDA:UniProtKB. 

Interpro

 IPR005375; UFM1. 

Pfam

 PF03671; Ufm1 

SMART

  

PROSITE

  

PRINTS