| Tag | Content |
|---|
| CPLM ID | CPLM-024290 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Rho guanine nucleotide exchange factor 37 |
Protein Synonyms/Alias | Protein 2-88; Scaffold protein tuba 3 |
Gene Name | Arhgef37 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 245 | INTHTLSKKTTRLSQ | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | May act as a guanine nucleotide exchange factor (GEF) (By similarity). |
Sequence Annotation | DOMAIN 30 213 DH.
DOMAIN 254 455 BAR.
DOMAIN 506 569 SH3 1.
DOMAIN 603 666 SH3 2. |
Keyword | Complete proteome; Guanine-nucleotide releasing factor; Reference proteome; Repeat; SH3 domain. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 676 AA |
Protein Sequence | MADFETDEAS SKSESPEQEG QGSEDKSLLH QRLAIRELID TEVSYLHTLR LCTSDIRGHL 60
QQLPPGDLDI LFSNIDDIIQ VSSRFLHGLQ ETACKEEKQA HLIGNLFLEF QEELEQVYKV 120
YCANYDQALL LVKAYQKEPE LQKEIQGIIE AAVPQAGPSG LSFLLVIPLQ RITKYPLLLQ 180
KILENTPADA SAHPVLQRAT SALQDVNSNI NEYKMRKEVA LKYTKVEQLS LRERLARINT 240
HTLSKKTTRL SQLLKQEAGL VPRTEDKEFD DLEERFQWVS LCVTELKSNV AAYMDNLEAF 300
LCFRPHERNL DIPGGAAEQY CSLARDLQLQ AFLQFKQRLT GLVWQPLCSL ARALVGPQNL 360
IKKRLDKLLD FERVEEKLLD VGSVTYEEEA ARHTYQALNS LIVAELPQFN HLVMQWLGQI 420
LRTFVVLQRD LADQVLRRAE SSMALLPHRH VSEPDFQKLL EDTLGQSSSQ LRHFRESFEK 480
VLPPSTSQPL LPGSEHQMQS LLTRYGPGKI YQVTSNINGT GTLDLTLPRG QIVALLQNKD 540
TKGNNSRWLV DTGGHRGYVP AGKLQLYHPI NPSEKEPRRQ TGMPEDYWLP TPEPTQPSVP 600
TVPTMSQVVA VYPFVARSTH ELSLQAGQPV TILEAQDKKG NPEWSLVEAN GQRGYVPSNF 660
LARTPSPTPR GWNLPS 676 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:InterPro. GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |