CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024570
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Putative UPF0609 protein C4orf27-like 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
28TVDVKKSKFCEADVSacetylation[1, 2]
28TVDVKKSKFCEADVSubiquitination[3]
151VGINEAKKNCIIVPNubiquitination[3]
250PETDADLKRICKTIVubiquitination[3]
322PLAYNLLKRNLFAEIubiquitination[3, 4]
Reference
 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 347 AA 
Protein Sequence
MVGGGWKRRP GAGAGPQCEK TVDVKKSKFC EADVSSDLRK EVENHYTLSL PEDFYHFWKF 60
CEELDSEKPA DPLSASLGLQ LVDPYNILAG KHKMKKKSTV PNFNLHWRFY YDPPEFQTII 120
IRDKLSATWG ISDRDSPDEL PVYVGINEAK KNCIIVPNGD NVFAAVKLYL MKKLKEVTDK 180
KKTNLFKNVD EKLTETAREL GYSLEQRTMK MKQRDKKVVT KTFHGTGLVP PVDKNVVGYR 240
ELPETDADLK RICKTIVEAA SDDERRKAFA PIQEMMTFVQ FANDECDYGM GLELGMDLFC 300
YGSHYFHKVA GQLLPLAYNL LKRNLFAEIM KDHLANRRKE NIDQFAA 347 
Gene Ontology
  
Interpro
 IPR019361; DUF2228_C2H2_APLF-like. 
Pfam
 PF10228; DUF2228 
SMART
  
PROSITE
  
PRINTS