CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032034
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cysteine-rich hydrophobic domain 1 protein 
Protein Synonyms/Alias
 cDNA FLJ53812, highly similar to Cysteine-rich hydrophobic domain 1 protein 
Gene Name
 CHIC1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
169RTRRSIQKLIEWENNubiquitination[1, 2, 3, 4, 5]
Reference
 [1] Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.
 Danielsen JM, Sylvestersen KB, Bekker-Jensen S, Szklarczyk D, Poulsen JW, Horn H, Jensen LJ, Mailand N, Nielsen ML.
 Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. [PMID: 21139048]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 217 AA 
Protein Sequence
MAEFDTISEL EEEEEEEAAT SSSSPSSSSS VSGPDDDEED EEEEEEEEEE EEEEEEEEEE 60
EAPPPPRVVS EEHLRRYAPD PVLVRGAGHI TVFGLSNKFD TEFPSVLTGK VAPEEFKTSI 120
GRVNACLKKA LPVNVKWLLC GCLCCCCTLG CSLWPVICLN KRTRRSIQKL IEWENNRLYH 180
KLALHWKLTK RKCETSNMME YVILIEFLPK YPIFRPD 217 
Gene Ontology
  
Interpro
 IPR019383; Golgin_A_7/ERF4. 
Pfam
 PF10256; Erf4 
SMART
  
PROSITE
  
PRINTS