CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031383
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycylpeptide N-tetradecanoyltransferase 
Protein Synonyms/Alias
  
Gene Name
 NMT2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
139MTLQRTMKLYRLPDVubiquitination[1]
259ALILAKSKGFDVFNAubiquitination[1]
278ENKTFLEKLKFGIGDubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity). 
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 310 AA 
Protein Sequence
MFRFDYSPEF LLWALRPPGW LLQWHCGVRV SSNKKLVGFI SAIPANIRIY DSVKKMVEIN 60
FLCVHKKLRS KRVAPVLIRE ITRRVNLEGI FQAVYTAGVV LPKPIATCRY WHRSLNPRKL 120
VEVKFSHLSR NMTLQRTMKL YRLPDVTKTS GLRPMEPKDI KSVRELINTY LKQFHLAPVM 180
DEEEVAHWFL PREHIIDTFV VESPNGKLTD FLSFYTLPST VMHHPAHKSL KAAYSFYNIH 240
TETPLLDLMS DALILAKSKG FDVFNALDLM ENKTFLEKLK FGIGDGNLQY YLYNWRCPGT 300
DSEKVGLVLQ 310 
Gene Ontology
 GO:0004379; F:glycylpeptide N-tetradecanoyltransferase activity; IEA:EC.
 GO:0006499; P:N-terminal protein myristoylation; IEA:InterPro. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR000903; MyristoylCoA_TrFase.
 IPR022677; MyristoylCoA_TrFase_C.
 IPR022678; MyristoylCoA_TrFase_CS.
 IPR022676; MyristoylCoA_TrFase_N. 
Pfam
 PF01233; NMT
 PF02799; NMT_C 
SMART
  
PROSITE
 PS00975; NMT_1
 PS00976; NMT_2 
PRINTS