UniProt Accession

 RPN9_YEAST; Q04062; D6VT56 

Genbank Protein ID

 U33007; BK006938 

Genbank Nucleotide ID

 AAB64853.1; DAA12266.1 

Protein Name

 26S proteasome regulatory subunit RPN9 

Protein Synonyms/Alias

 Proteasome non-ATPase subunit 7 

Gene Name

 RPN9 

Gene Synonyms/Alias

 NAS7; YDR427W; D9461.14 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
53	TKFFDDAKSTPLRLR	ubiquitination	[1]
72	FVSKFYDKINQLSVV	acetylation	[2]
379	EWNDQVEKLGKKMEA	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. 

Sequence Annotation

 DOMAIN 282 352 PCI.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Proteasome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 393 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:SGD.
 GO:0008541; C:proteasome regulatory particle, lid subcomplex; IDA:SGD.
 GO:0034515; C:proteasome storage granule; IDA:SGD.
 GO:0005198; F:structural molecule activity; IMP:SGD.
 GO:0043248; P:proteasome assembly; IMP:SGD.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD. 

Interpro

 IPR000717; PCI_dom.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF01399; PCI 

SMART

 SM00088; PINT 

PROSITE

  

PRINTS