| Tag | Content |
|---|
| CPLM ID | CPLM-007820 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Actin-interacting protein 1 |
Protein Synonyms/Alias | |
Gene Name | AIP1 |
Gene Synonyms/Alias | YMR092C; YM9582.17C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 39 | AIAYPCGKSAFVRCL | ubiquitination | [1] | | 294 | VQKWTLDKQQLGNQQ | ubiquitination | [1] | | 608 | SGADACIKRWNVVLE | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in the depolymerization of actin filaments. Enhances the filament disassembly activity of cofilin and restricts cofilin localization to cortical actin patches. |
Sequence Annotation | REPEAT 1 45 WD 1.
REPEAT 46 94 WD 2.
REPEAT 95 146 WD 3.
REPEAT 147 189 WD 4.
REPEAT 190 235 WD 5.
REPEAT 236 280 WD 6.
REPEAT 281 325 WD 7.
REPEAT 326 363 WD 8.
REPEAT 364 399 WD 9.
REPEAT 400 433 WD 10.
REPEAT 434 473 WD 11.
REPEAT 474 516 WD 12.
REPEAT 517 569 WD 13.
REPEAT 570 611 WD 14. |
Keyword | 3D-structure; Actin-binding; Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 615 AA |
Protein Sequence | MSSISLKEII PPQPSTQRNF TTHLSYDPTT NAIAYPCGKS AFVRCLDDGD SKVPPVVQFT 60
GHGSSVVTTV KFSPIKGSQY LCSGDESGKV IVWGWTFDKE SNSVEVNVKS EFQVLAGPIS 120
DISWDFEGRR LCVVGEGRDN FGVFISWDSG NSLGEVSGHS QRINACHLKQ SRPMRSMTVG 180
DDGSVVFYQG PPFKFSASDR THHKQGSFVR DVEFSPDSGE FVITVGSDRK ISCFDGKSGE 240
FLKYIEDDQE PVQGGIFALS WLDSQKFATV GADATIRVWD VTTSKCVQKW TLDKQQLGNQ 300
QVGVVATGNG RIISLSLDGT LNFYELGHDE VLKTISGHNK GITALTVNPL ISGSYDGRIM 360
EWSSSSMHQD HSNLIVSLDN SKAQEYSSIS WDDTLKVNGI TKHEFGSQPK VASANNDGFT 420
AVLTNDDDLL ILQSFTGDII KSVRLNSPGS AVSLSQNYVA VGLEEGNTIQ VFKLSDLEVS 480
FDLKTPLRAK PSYISISPSE TYIAAGDVMG KILLYDLQSR EVKTSRWAFH TSKINAISWK 540
PAEKGANEEE IEEDLVATGS LDTNIFIYSV KRPMKIIKAL NAHKDGVNNL LWETPSTLVS 600
SGADACIKRW NVVLE 615 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |