Tag | Content |
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CPLM ID | CPLM-027378 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Histone acetyltransferase GCN5, putative |
Protein Synonyms/Alias | |
Gene Name | gcn5 |
Gene Synonyms/Alias | PF08_0034 |
Created Date | July 27, 2013 |
Organism | Plasmodium falciparum (isolate 3D7) |
NCBI Taxa ID | 36329 |
Lysine Modification | Position | Peptide | Type | References |
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637 | NNEFENIKRVHSNSS | acetylation | [1] | 709 | STNFVNGKYISKLNN | acetylation | [1] | 1317 | IKPQVIYKGINYFAD | acetylation | [1] | 1344 | GLLEVGWKKETREIT | acetylation | [1] | 1345 | LLEVGWKKETREITK | acetylation | [1] |
|
Reference | [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development. Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L. Mol Microbiol. 2013 Aug;89(4):660-75. [ PMID: 23796209] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1465 AA |
Protein Sequence | MDYLIRNNEY CNVLYDGNEL LRKRKINFDN EICPYKMNYW NNYNNNINID NDNMNNEIVN 60 EEFENTYNNI NNNMYYLLGK EDMDEPRLCN KKRNVYNENF KNNLEYDENV NNYDNDNSSN 120 ISYKFINNEC DKMKKSGEGT QENNDNENNN NDESNNNNNN NNNESNNNNN NNESNNNNNN 180 NNNNESNNNN NNNESNNNNH GNNNNSSNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 240 DKNEDDENTT GKGKKTEVKK RAGRKRNDST MYANSNTMLK NNFLQNNKMI YNNMDHINDT 300 NEQDKFLYEQ RKMMMNNKME NMGPNMNMTN KNYFQTVNNM KMNVENNKNL IGINTNNMNN 360 YQNNINSINT NMNIPKNKNL HSNKQMMFMN NNMNIHGKTN KLNDMARMNS INFNEENKMS 420 VMNDDTRMDN KMRDIMKSGG MEVHLKNEES LYMNNMYNMN SNNPNNIPRI STMNIAKPMN 480 NFNNMNMPIN NMNAYNNHMI NSYNNMMMTN NMNNINNINN INHINNNNNS NNNNNSNNSN 540 NNINFGQHIQ GVQFMNPNMN NDMNSNMNNI NNNQMFLNNN QNNAHVHMVN NMNLNPSGNN 600 SFFNNSNKHL NMMTMSSKNK KNAILKNTEN NEFENIKRVH SNSSNYNNNN NNNSDSNNKK 660 SIKMNSNENN NTTTTIIKNI RVENIKFNES VNLKNIDGLD LSTNFVNGKY ISKLNNDEKI 720 YNVVHSIVKD SLKDCLVDFY NNANYIFKDK LDFVCNSNTP TCNNINDLED NKKDDGHVDK 780 QNYSLEKKDN EEHTNNNSDP IMDGVELDVK KISEKKEDQI EKDKPKNDNT KNDNTKEDKN 840 QNDDNKTNTS IPKTPKNEVK NVITSSLLSS FNIFSAFSNS NTPNSKKNKY DEEEEKEEKE 900 EEEENNKCND KDDEDKNKSP QNEDNKNITN DNNDNNNNNV DKENNLKESI DNLGNVDTDN 960 NIKRDVLNYN NIEENEQSRE YILIEITKSI CSIINLQQLM PVNTRLANPN LIYDPNYETI 1020 YSKWKTFLRK EQSSGNLISN CFSRDFLHTI LLCNYVTIIE DLRKTAVKKK LKYFFLHLCL 1080 ESGISINVAL MLFINATKQS DKLQSLLPSE TGLGYLHRDA GGAKEENMGI ITFECITNDR 1140 EPDHLIKLIT LKNIFSRQLP KMPREYIVRL VFDRNHYTFC LLKKNTVIGG VCFRPYFEQK 1200 FAEIAFLAVT STEQVKGYGT RLMNHLKEHV KKFGIEYFLT YADNFAIGYF RKQGFSQKIS 1260 MPKERWFGYI KDYDGGTLME CYIFPNINYL RLSEMLYEQK KAVKKAIHFI KPQVIYKGIN 1320 YFADNKGAAL HPSTIPGLLE VGWKKETREI TKKVQHKEVQ LKDQILGVLD YLEKQQSAWP 1380 FLKPVSLSEA PDYYDIIKEP TDILTMRRKA RHGDYKTKED FGIELKRMFD NCRLYNAPTT 1440 IYFKYANELQ TLIWPKYEAI TDTAK 1465 |
Gene Ontology | GO:0004402; F:histone acetyltransferase activity; ISS:GeneDB_Pfalciparum. GO:0006355; P:regulation of transcription, DNA-dependent; ISS:GeneDB_Pfalciparum. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |