UniProt Accession

 UPP_BACSU; P39149 

Genbank Protein ID

 Z38002; AL009126 

Genbank Nucleotide ID

 CAA86111.1; CAB15706.1 

Protein Name

 Uracil phosphoribosyltransferase 

Protein Synonyms/Alias

 UMP pyrophosphorylase; UPRTase 

Gene Name

 upp 

Gene Synonyms/Alias

 BSU36890; ipc-35d 

Created Date

 July 27, 2013 

Organism

 Bacillus subtilis (strain 168) 

NCBI Taxa ID

 224308 

Lysine Modification

Position	Peptide	Type	References
110	YRDPETLKPVEYYVK	acetylation	[1]
148	VEAIHSLKKRGAKNI	acetylation	[1]

Reference

 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 

Functional Description

 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity). 

Sequence Annotation

 REGION 131 139 5-phospho-alpha-D-ribose 1-diphosphate
 REGION 199 201 Uracil binding (By similarity).
 BINDING 79 79 5-phospho-alpha-D-ribose 1-diphosphate
 BINDING 104 104 5-phospho-alpha-D-ribose 1-diphosphate
 BINDING 194 194 Uracil; via amide nitrogen (By
 BINDING 200 200 5-phospho-alpha-D-ribose 1-diphosphate  

Keyword

 Allosteric enzyme; Complete proteome; Glycosyltransferase; GTP-binding; Magnesium; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 209 AA 

Protein Sequence

Gene Ontology

 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0004845; F:uracil phosphoribosyltransferase activity; IEA:HAMAP.
 GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
 GO:0006223; P:uracil salvage; IEA:InterPro. 

Interpro

 IPR000836; PRibTrfase_dom.
 IPR005765; Ura_phspho_trans. 

Pfam

 PF00156; Pribosyltran 

SMART

  

PROSITE

  

PRINTS