| Tag | Content |
|---|
| CPLM ID | CPLM-015637 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Chondroitin sulfate proteoglycan 5 |
Protein Synonyms/Alias | Acidic leucine-rich EGF-like domain-containing brain protein; Neuroglycan C |
Gene Name | Cspg5 |
Gene Synonyms/Alias | Caleb; Ngc |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 527 | HKIQDPLKSRLKEEE | ubiquitination | [1] | | 531 | DPLKSRLKEEESFNI | ubiquitination | [1] | | 545 | IQNSMSPKLEGGKGD | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. |
Sequence Annotation | DOMAIN 371 413 EGF-like.
REGION 265 301 Interaction with TNC and TNR.
REGION 442 460 Interaction with GOPC (By similarity).
CARBOHYD 57 57 N-linked (GlcNAc...) (Potential).
CARBOHYD 76 76 O-linked (GalNAc...) (Potential).
CARBOHYD 123 123 O-linked (Xyl...) (chondroitin sulfate).
CARBOHYD 132 132 O-linked (GalNAc...) (Potential).
CARBOHYD 143 143 O-linked (GalNAc...) (Potential).
CARBOHYD 144 144 O-linked (GalNAc...) (Potential).
CARBOHYD 153 153 O-linked (GalNAc...) (Potential).
CARBOHYD 155 155 O-linked (GalNAc...) (Potential).
CARBOHYD 156 156 O-linked (GalNAc...) (Potential).
CARBOHYD 160 160 O-linked (GalNAc...) (Potential).
CARBOHYD 235 235 O-linked (GalNAc...) (Potential).
CARBOHYD 355 355 N-linked (GlcNAc...) (Potential).
CARBOHYD 367 367 N-linked (GlcNAc...) (Potential).
DISULFID 374 387 By similarity.
DISULFID 381 397 By similarity.
DISULFID 399 412 By similarity. |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Developmental protein; Differentiation; Disulfide bond; EGF-like domain; Endoplasmic reticulum; Glycoprotein; Golgi apparatus; Growth regulation; Membrane; Neurogenesis; Phosphoprotein; Proteoglycan; Reference proteome; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 566 AA |
Protein Sequence | MGRAGGGGPD WGPPPVLLLL GVTLVLTAGA VPARETGSAI EAEELVRSSL AWESRANDTR 60
EEAGLPAAGE DETSWTERGS EMAAVGPGVG PEEALEASAA VTGTAWLEAD GPGLGGVTAE 120
AGSGDAQTLP ATLQAPDEAL GSSTMPPAIP EATETSGPPS PAVHDKPSVG PELPKEIPLE 180
VRLNLGGSTP EPTFPLQGTL ETQPASDIID IDYFEGLDSE GRGADMGSFP GSPGTSENHP 240
DTEGETPSWS LLDLYDDFTP FDESDFYPTT SFYDDLEEEE EEEEDKDTVG GGDLEDENDL 300
LLPSQKPGVG PGTGQPTNRW HAVPPQHTLG MVPGSSISLR PRPGDPGKDL ASGENGTECR 360
VGFVRHNGSC RSVCDLFPSY CHNGGQCYLV ENIGAFCRCN TQDYIWHKGM RCESIITDFQ 420
VMCVAVGSAA LVLLLLFMMT VFFAKKLYLL KTENTKLRRT NKFRTPSELH NDNFSLSTIA 480
EGSHPNVRKF CDTPRVSSPH ARALAHYDNI VCQDDPSAPH KIQDPLKSRL KEEESFNIQN 540
SMSPKLEGGK GDQDDLGVNC LQNNLT 566 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0031103; P:axon regeneration; IEA:Compara. GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. GO:0050804; P:regulation of synaptic transmission; IMP:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |