UniProt Accession

 MAGA4_HUMAN; P43358; Q14798 

Genbank Protein ID

 U10687; U10688; U10340; D32075; D32077; AF274855; BC017723 

Genbank Nucleotide ID

 AAA68871.1; AAA68872.1; AAA19007.1; BAA06841.1; BAA06843.1; AAH17723.1 

Protein Name

 Melanoma-associated antigen 4 

Protein Synonyms/Alias

 Cancer/testis antigen 1.4; CT1.4; MAGE-4 antigen; MAGE-41 antigen; MAGE-X2 antigen 

Gene Name

 MAGEA4 

Gene Synonyms/Alias

 MAGE4 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
245	TVYGEPRKLLTQDWV	ubiquitination	[1]
286	LAETSYVKVLEHVVR	acetylation	[2]
286	LAETSYVKVLEHVVR	ubiquitination	[1]

Reference

 [1] Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.
 Danielsen JM, Sylvestersen KB, Bekker-Jensen S, Szklarczyk D, Poulsen JW, Horn H, Jensen LJ, Mailand N, Nielsen ML.
 Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. [PMID: 21139048]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 

Functional Description

 Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. 

Sequence Annotation

 DOMAIN 110 309 MAGE.  

Keyword

 3D-structure; Complete proteome; Polymorphism; Reference proteome; Tumor antigen. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 317 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR002190; MAGE.
 IPR021072; Melanoma_ass_antigen_N. 

Pfam

 PF01454; MAGE
 PF12440; MAGE_N 

SMART

  

PROSITE

 PS50838; MAGE 

PRINTS