CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027998
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG6178 
Protein Synonyms/Alias
 GM05240p; RE32988p 
Gene Name
 CG6178, Dmel_CG6178 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
71RLAYILQKLGVKQNDacetylation[1]
149ASKNKFVKGIIALSGacetylation[1]
162SGTSKKFKNIYDLKEacetylation[1]
175KELMEDEKFKTQPDFacetylation[1]
266ARLVYLPKFEEKLFLacetylation[1]
278LFLSAIEKYRVMMAFacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Ligase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 544 AA 
Protein Sequence
MTSKLLPGNI VYGGPVTERQ AQDSRSLGQY ILDKYKSFGD RTVLVDAVNG VEYSASFMHK 60
SIVRLAYILQ KLGVKQNDVV GLSSENSVNF ALAMFAGLAV GATVAPLNVT YSDREVDHAI 120
NLSKPKIIFA SKITIDRVAK VASKNKFVKG IIALSGTSKK FKNIYDLKEL MEDEKFKTQP 180
DFTSPAANKD EDVSLIVCSS GTTGLPKGVQ LTQMNLLATL DSQIQPTVIP MEEVTLLTVI 240
PWFHAFGCLT LITTACVGAR LVYLPKFEEK LFLSAIEKYR VMMAFMVPPL MVFLAKHPIV 300
DKYDLSSLMV LLCGAAPLSR ETEDQIKERI GVPFIRQGYG LSESTLSVLV QNDEFCKPGS 360
VGVLKVGIYA KVIDPDTGKL LGANERGELC FKGDGIMKGY IGDTKSTQTA IKDGWLHTGD 420
IGYYDDDFEF FIVDRIKELI KYKGYQVPPA EIEALLLTND KIKDAAVIGK PDEEAGELPL 480
AFVVKQANVQ LTENEVIQFV NDNASPAKRL RGGVIFVDEI PKNPSGKILR RILREMLKKQ 540
KSKL 544 
Gene Ontology
 GO:0004321; F:fatty-acyl-CoA synthase activity; IDA:FlyBase.
 GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:FlyBase.
 GO:0046949; P:fatty-acyl-CoA biosynthetic process; IDA:FlyBase. 
Interpro
 IPR020845; AMP-binding_CS.
 IPR000873; AMP-dep_Synth/Lig.
 IPR025110; DUF4009. 
Pfam
 PF00501; AMP-binding
 PF13193; DUF4009 
SMART
  
PROSITE
 PS00455; AMP_BINDING 
PRINTS