UniProt Accession

 ERGI3_HUMAN; Q9Y282; Q5JWS3; Q6ZWP7; Q9H276; Q9P1L3 

Genbank Protein ID

 AF308298; AF151812; AK074550; AF077030; AL121586; AL121586; BC009765; BC014014; AF116614 

Genbank Nucleotide ID

 AAG48265.1; AAD34049.1; BAC11054.1; AAD27763.1; CAB89412.1; CAI42842.1; AAH09765.1; AAH14014.1; AAF71038.1 

Protein Name

 Endoplasmic reticulum-Golgi intermediate compartment protein 3 

Protein Synonyms/Alias

 Serologically defined breast cancer antigen NY-BR-84 

Gene Name

 ERGIC3 

Gene Synonyms/Alias

 C20orf47; ERV46; SDBCAG84; CGI-54; PRO0989 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
8	MEALGKLKQFDAYPK	ubiquitination	[1, 2]
15	KQFDAYPKTLEDFRV	ubiquitination	[1, 2]
174	RRRGWAFKNPDTIEQ	ubiquitination	[2]
190	RREGFSQKMQEQKNE	ubiquitination	[2]
337	MMVKLTEKHRSFTHF	ubiquitination	[2]
381	QKKIDLGKTT*****	ubiquitination	[2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Possible role in transport between endoplasmic reticulum and Golgi (By similarity). 

Sequence Annotation

 CARBOHYD 241 241 N-linked (GlcNAc...).
 CARBOHYD 266 266 N-linked (GlcNAc...) (Potential).  

Keyword

 Alternative splicing; Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Glycoprotein; Golgi apparatus; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 383 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 

Interpro

 IPR012936; Erv_C. 

Pfam

 PF07970; COPIIcoated_ERV 

SMART

  

PROSITE

  

PRINTS