UniProt Accession

 ZNF92_HUMAN; Q03936; A6NNF9; Q8N492; Q8NB35 

Genbank Protein ID

 AK091618; AC092685; BC036439; BC040594; M61872 

Genbank Nucleotide ID

 BAC03708.1; AAH36439.1; AAH40594.1; AAA58673.1 

Protein Name

 Zinc finger protein 92 

Protein Synonyms/Alias

 Zinc finger protein HTF12 

Gene Name

 ZNF92 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
97	SIKDSFQKVILRTYG	ubiquitination	[1]
105	VILRTYGKYGHENLQ	ubiquitination	[1]
124	HKSVDACKVYKGGYN	ubiquitination	[1]
127	VDACKVYKGGYNGLN	ubiquitination	[1]
202	HTREYSYKCEECGKA	ubiquitination	[1]
236	YKCEECGKAFNRSSN	ubiquitination	[1]
286	HTEEKPYKCEECGKA	ubiquitination	[1]
358	NQFSNLTKHKIIHTG	ubiquitination	[1]
513	GKSYKCEKCGNAFNQ	ubiquitination	[1]
575	ECGRAFNKSSNYTKE	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May be involved in transcriptional regulation. 

Sequence Annotation

 DOMAIN 4 75 KRAB.
 ZN_FING 145 167 C2H2-type 1; degenerate.
 ZN_FING 173 195 C2H2-type 2; degenerate.
 ZN_FING 201 223 C2H2-type 3.
 ZN_FING 229 251 C2H2-type 4.
 ZN_FING 257 279 C2H2-type 5.
 ZN_FING 285 307 C2H2-type 6.
 ZN_FING 313 335 C2H2-type 7.
 ZN_FING 341 363 C2H2-type 8.
 ZN_FING 369 391 C2H2-type 9.
 ZN_FING 397 419 C2H2-type 10.
 ZN_FING 425 447 C2H2-type 11.
 ZN_FING 453 475 C2H2-type 12.
 ZN_FING 481 503 C2H2-type 13.
 ZN_FING 509 531 C2H2-type 14; degenerate.
 ZN_FING 537 559 C2H2-type 15; degenerate.
 ZN_FING 563 586 C2H2-type 16; degenerate.  

Keyword

 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 586 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; NAS:UniProtKB.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
 GO:0008270; F:zinc ion binding; NAS:UniProtKB.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 

Pfam

 PF01352; KRAB 

SMART

 SM00349; KRAB
 SM00355; ZnF_C2H2 

PROSITE

 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 

PRINTS