UniProt Accession

 NTF2_MOUSE; P61971; P13662; Q3TI35 

Genbank Protein ID

 AK002461; AK012500; AK020512; AK028410; AK051049; AK168026; BC003955; BC083165; BC086773 

Genbank Nucleotide ID

 BAB22117.1; BAB28283.1; BAB32122.1; BAC25936.1; BAC34511.1; BAE40011.1; AAH03955.1; AAH83165.1; AAH86773.1 

Protein Name

 Nuclear transport factor 2 

Protein Synonyms/Alias

 NTF-2 

Gene Name

 Nutf2 

Gene Synonyms/Alias

 Ntf2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
4	****MGDKPIWEQIG	acetylation	[1]
55	GKAAIVEKLSSLPFQ	acetylation	[2]
55	GKAAIVEKLSSLPFQ	ubiquitination	[3]

Reference

 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity). 

Sequence Annotation

 DOMAIN 10 121 NTF2.
 MOD_RES 4 4 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 127 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 

Interpro

 IPR002075; NTF2.
 IPR018222; Nuclear_transport_factor_2_euk. 

Pfam

 PF02136; NTF2 

SMART

  

PROSITE

 PS50177; NTF2_DOMAIN 

PRINTS