UniProt Accession

 B4DPY8_HUMAN; B4DPY8; E7EV69 

Genbank Protein ID

 AE000658; AL161747; AK298555 

Genbank Nucleotide ID

 BAG60750.1 

Protein Name

 TOX high mobility group box family member 4 

Protein Synonyms/Alias

 cDNA FLJ54372, highly similar to Epidermal Langerhans cell protein LCP1 

Gene Name

 TOX4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
184	TVVVEAGKKQKAPKK	acetylation	[1, 2]
185	VVVEAGKKQKAPKKR	ubiquitination	[2]
219	RDTQAAIKGQNPNAT	ubiquitination	[3]

Reference

 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 598 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:HPA. 

Interpro

 IPR009071; HMG_box_dom. 

Pfam

 PF00505; HMG_box 

SMART

 SM00398; HMG 

PROSITE

 PS50118; HMG_BOX_2 

PRINTS