CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038915
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 IQ motif and SEC7 domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 Iqsec3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
971LGSDEMQKFVEDLKEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1194 AA 
Protein Sequence
MESLLENPVR AVLYLKELTA IVQNQQSLIH TQRQRIDELE RRLDELSAEN RSLWEHQQLL 60
QAQPPPGLVP PPSAPLPAPA ATAPAATAAQ EPLQDHGQLI PATPEPPLQH HGQLLAQPQP 120
APSSRVQTPQ SPHQHPVAPG AVADKEKERP SSCCAAAGAL LQHASPAALG KGVLSRRPKN 180
ETVLHQFCCP AADTEQKPAC SDLASQSDGS CAQAGGGMED SVVAAVAAGR PSAHAPKAQA 240
PELQQEEERP GAVGSPRAGP LRAASPGQQQ PALATALCSH TPAASEYELS LDLKNKQIEM 300
LEHKYGGHLV SRRAACTIQT AFRQYQLSKN FEKIRNSLLE SRLPRRISLR KVRAPTAESL 360
VAEKALLESC GLLGLPLGRS PSLPPTFAGS LTELEDSFTE QVQSLAKSID DALSTWSLKT 420
MCSLQESGAY QLHQALHPSA GQPGLETEAA REPDSGPGSG DEAGSLPQGH SGTLMMAFRD 480
VTVQIANQNI SVSSSTALSV ANCLGAQTAQ ATAEPAAVQT EQGDAATQEV SEVPASELMD 540
PPVEDSEAAE SGAQSAHEPT VAEAVVEEAV ATEAEEEEEG AGQAGKGAEA EVGDNSEQLS 600
SSSASTKSAK SGSEVSAAAS KEALQAVILS LPRYHCENPA SCRSPTLSTD TLRKRLYRIG 660
LNLFNINPDK GIQFLISRGF IPDTPIGVAH FLLQRKGLSR QMIGEFLGNS KKQFNRDVLD 720
CVVDEMDFSN MELDEALRKF QAHIRVQGEA QKVERLIEAF SQRYCMCNPE VVQQFHNPDT 780
IFILAFAIIL LNTDMYSPNI KPDRKMMLED FIRNLRGVDD GADIPRELVV GIYERIQQKE 840
LKSNEDHVTY VTKVEKSIVG MKTVLSMPHR RLVCCSRLFE VTDVNKLQKQ AAHQREVFLF 900
NDLLVILKLC PKKKSSFTYT FCKAVGLLGM RFHLFENEYY SHGITLATPL SGSEKKQVLH 960
FCALGSDEMQ KFVEDLKESI AEVTELEQIR IEWELERQQG TKTLSARSAG AQGDPQSKQG 1020
SPTAKREAMA GEKATESSGE VSIHNRLQTF QHSPKLGVER GAPAPSPPTS PPPPLPPDPQ 1080
PSPLREQPPP LPLPPPTPPG TLVQCQQIVK VIVLDKPCLA RMEPLLSQAL SCYASSSSDS 1140
CGSTPLRGPG SPVKVIHQPP LPPPPPPYNH PHQFCPPGSL LLRRRYSSGS RSLV 1194 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0060077; C:inhibitory synapse; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0045211; C:postsynaptic membrane; IEA:Compara.
 GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR000904; Sec7.
 IPR023394; SEC7_alpha_orthog. 
Pfam
 PF01369; Sec7 
SMART
 SM00233; PH
 SM00222; Sec7 
PROSITE
 PS50096; IQ
 PS50190; SEC7 
PRINTS