CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028307
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CDW13/WDR61 
Protein Synonyms/Alias
 WD repeat domain 61, isoform CRA_c 
Gene Name
 Wdr61 
Gene Synonyms/Alias
 mCG_9684 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
29VAWETNKKENIETVVubiquitination[1]
97LWDLENGKQMKSIDAubiquitination[1]
139IFGVESGKKEYSLDTubiquitination[1]
140FGVESGKKEYSLDTRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 305 AA 
Protein Sequence
MTNQYSILFK QEQAHDDAIW SVAWETNKKE NIETVVTGSL DDLVKVWKWR DERLELQWSL 60
EGHQLGVVSV DISHTLPIAA SSSLDAHIRL WDLENGKQMK SIDAGPVDAW TLAFSPDSQY 120
LATGTHMGKV NIFGVESGKK EYSLDTRGKF ILSIAYSPDG KYLASGAIDG IINIFDIATG 180
KLLHTLEGHA MPIRSLTFSP DSQLLVTASD DGYIKIYDVQ HANLAGTLSG HASWVLNVAF 240
CPDDTHFVSS SSDKSVKVWD VGTRTCIHTF FDHQDQVWGV KYNGNGSKIV SVGDDQEIHV 300
YDCPI 305 
Gene Ontology
 GO:0016593; C:Cdc73/Paf1 complex; IEA:Compara.
 GO:0055087; C:Ski complex; IEA:Compara.
 GO:0035327; C:transcriptionally active chromatin; IEA:Compara.
 GO:0080182; P:histone H3-K4 trimethylation; IEA:Compara.
 GO:0045638; P:negative regulation of myeloid cell differentiation; IEA:Compara.
 GO:0051571; P:positive regulation of histone H3-K4 methylation; IEA:Compara.
 GO:2001162; P:positive regulation of histone H3-K79 methylation; IEA:Compara.
 GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.