UniProt Accession

 WDR13_HUMAN; Q9H1Z4; Q06DX1; Q9BUL7; Q9NWW4 

Genbank Protein ID

 AF329819; DQ907252; AF149817; AC115618; CH471224; BC002507; BC080579; AK000570 

Genbank Nucleotide ID

 AAG47845.3; ABI93266.1; AAK13247.1; EAW50760.1; AAH02507.2; AAH80579.1; BAA91261.1 

Protein Name

 WD repeat-containing protein 13 

Protein Synonyms/Alias

  

Gene Name

 WDR13 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
380	LINACLNKLLLYRVV	ubiquitination	[1]
396	NEGTLQLKRSFPIEQ	ubiquitination	[2, 3]

Reference

 [1] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

 REPEAT 170 210 WD 1.
 REPEAT 215 254 WD 2.
 REPEAT 302 341 WD 3.
 REPEAT 406 446 WD 4.
 REPEAT 451 484 WD 5.
 MOD_RES 70 70 Phosphoserine.
 MOD_RES 116 116 Phosphoserine (By similarity).  

Keyword

 Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; WD repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 485 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 

Interpro

 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 

Pfam

 PF00400; WD40 

SMART

 SM00320; WD40 

PROSITE

 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 

PRINTS