CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011415
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Peroxisomal adenine nucleotide transporter 1 
Protein Synonyms/Alias
  
Gene Name
 ANT1 
Gene Synonyms/Alias
 YPR128C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
47SEDSNEGKVLPNRRYubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Adenine nucleotide transporter involved in the uniport of ATP and adenine nucleotide hetero-exchange transport between the cytosol and the peroxisomal lumen. This transport is accompanied by a proton transport from the peroxisomal lumen to the cytosol. Transport of ATP into the peroxisome is required for beta-oxidation of medium-chain fatty acids. Required for growth on medium-chain fatty acids, pH gradient formation in peroxisomes and for normal peroxisome proliferation. 
Sequence Annotation
 REPEAT 1 101 Solcar 1.
 REPEAT 122 208 Solcar 2.
 REPEAT 220 304 Solcar 3.  
Keyword
 Complete proteome; Hydrogen ion transport; Ion transport; Membrane; Peroxisome; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 328 AA 
Protein Sequence
MLTLESALTG AVASAMANIA VYPLDLSKTI IQSQVSPSSS EDSNEGKVLP NRRYKNVVDC 60
MINIFKEKGI LGLYQGMTVT TVATFVQNFV YFFWYTFIRK SYMKHKLLGL QSLKNRDGPI 120
TPSTIEELVL GVAAASISQL FTSPMAVVAT RQQTVHSAES AKFTNVIKDI YRENNGDITA 180
FWKGLRTGLA LTINPSITYA SFQRLKEVFF HDHSNDAGSL SAVQNFILGV LSKMISTLVT 240
QPLIVAKAML QSAGSKFTTF QEALLYLYKN EGLKSLWKGV LPQLTKGVIV QGLLFAFRGE 300
LTKSLKRLIF LYSSFFLKHN GQRKLAST 328 
Gene Ontology
 GO:0005779; C:integral to peroxisomal membrane; IDA:SGD.
 GO:0000295; F:adenine nucleotide transmembrane transporter activity; IDA:SGD.
 GO:0015867; P:ATP transport; IDA:SGD.
 GO:0006635; P:fatty acid beta-oxidation; IMP:SGD.
 GO:0007031; P:peroxisome organization; IMP:SGD.
 GO:0015992; P:proton transport; IEA:UniProtKB-KW. 
Interpro
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF00153; Mito_carr 
SMART
  
PROSITE
 PS50920; SOLCAR 
PRINTS