UniProt Accession

 GPHRC_HUMAN; A6NKF9 

Genbank Protein ID

 AL356004 

Genbank Nucleotide ID

 CAI17085.1 

Protein Name

 Putative Golgi pH regulator C 

Protein Synonyms/Alias

 Protein GPR89C 

Gene Name

 GPR89C 

Gene Synonyms/Alias

 GPHRC 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
68	TMDMIISKKKRMAMA	ubiquitination	[1, 2]
69	MDMIISKKKRMAMAR	ubiquitination	[3]
82	ARRTMFQKGEVHNKP	ubiquitination	[3]
88	QKGEVHNKPSGFWGM	ubiquitination	[3]
137	TADLYATKERIEYSK	ubiquitination	[1, 2]
144	KERIEYSKTFKGKYF	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

 CARBOHYD 45 45 N-linked (GlcNAc...) (Potential).
 CARBOHYD 108 108 N-linked (GlcNAc...) (Potential).  

Keyword

 Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 320 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR025969; ABA_GPCR_dom.
 IPR022535; Golgi_pH-regulator_cons_dom.
 IPR015672; GPCR89-rel. 

Pfam

 PF12430; ABA_GPCR
 PF12537; DUF3735 

SMART

  

PROSITE

  

PRINTS