UniProt Accession

 RAB7L_HUMAN; O14966; B4E1K3; C9JE77 

Genbank Protein ID

 D84488; AK308359; AK303879; AC119673; BC002585 

Genbank Nucleotide ID

 BAA22160.1; BAG64815.1; AAH02585.1 

Protein Name

 Ras-related protein Rab-7L1 

Protein Synonyms/Alias

 Rab-7-like protein 1 

Gene Name

 RAB7L1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
20	VGDAAVGKTSLVQRY	ubiquitination	[1]
34	YSQDSFSKHYKSTVG	ubiquitination	[1]
103	FSNSQRWKQDLDSKL	ubiquitination	[1]
126	PCLLLANKCDLSPWA	ubiquitination	[2]
144	DQIDRFSKENGFTGW	ubiquitination	[1]
157	GWTETSVKENKNINE	ubiquitination	[1]
172	AMRVLIEKMMRNSTE	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

 NP_BIND 14 21 GTP (By similarity).
 NP_BIND 63 67 GTP (By similarity).
 NP_BIND 125 128 GTP (By similarity).
 MOTIF 36 44 Effector region (By similarity).
 LIPID 202 202 S-geranylgeranyl cysteine (By
 LIPID 203 203 S-geranylgeranyl cysteine (By  

Keyword

 Alternative splicing; Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding; Prenylation; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 203 AA 

Protein Sequence

Gene Ontology

 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; TAS:ProtInc.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 

Pfam

 PF00071; Ras 

SMART

 SM00175; RAB 

PROSITE

 PS51419; RAB 

PRINTS

 PR00449; RASTRNSFRMNG.