UniProt Accession

 DLRB1_RAT; P62628; O88567; Q9D812 

Genbank Protein ID

 AF073839; AY026512; BC058437 

Genbank Nucleotide ID

 AAC25580.2; AAK18711.1; AAH58437.1 

Protein Name

 Dynein light chain roadblock-type 1 

Protein Synonyms/Alias

 Bithoraxoid-like protein; BLP; robl/LC7-like protein; Dynein light chain 2A, cytoplasmic; Dynein-associated protein Km23 

Gene Name

 Dynlrb1 

Gene Synonyms/Alias

 Dncl2a; Dnlc2a 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
9	AEVEETLKRLQSQKG	acetylation	[1]
9	AEVEETLKRLQSQKG	ubiquitination	[2]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine.  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Dynein; Microtubule; Motor protein; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 96 AA 

Protein Sequence

Gene Ontology

 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005868; C:cytoplasmic dynein complex; ISS:UniProtKB.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:UniProtKB-KW.
 GO:0008090; P:retrograde axon cargo transport; NAS:UniProtKB.
 GO:0007632; P:visual behavior; IDA:UniProtKB. 

Interpro

 IPR004942; Dynein_light-rel.
 IPR016561; Dynein_light_roadblock-type. 

Pfam

 PF03259; Robl_LC7 

SMART

 SM00960; Robl_LC7 

PROSITE

  

PRINTS