CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035035
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Arhgap26 
Protein Synonyms/Alias
 Rho GTPase activating protein 26 (Predicted) 
Gene Name
 Arhgap26 
Gene Synonyms/Alias
 Arhgap26_predicted; rCG_49509 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
121TPLEKFRKEQIGAARacetylation[1]
454KTVTSALKTYLRMLPubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTPase activation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 761 AA 
Protein Sequence
MGLPALEFSD CCLDSPHFRE TLKSHEAELD KTNKFIKELI KDGKSLISAL KNLSSAKRKF 60
ADSLNEFKFQ CIGDAETDDE MCIARSLQEF ATVLRNLEDE RSRMIENASE VLITPLEKFR 120
KEQIGAAREA KKKYDKETEK YCGTLEKHLN LSSKKKESQL QEADSQVDLV RQHFYEVSLE 180
YVFKVQEVQE RKMFEFVEPL LAFLQGLFTF YHHGYELAKD FGDFKTQLTI SIQNTRNRFE 240
GTRSEVESLM KKMKENPLEH KTISPYTMEG YLYVQEKRHF GTSWVKHYCT YQRDSKQITM 300
VPFDQKSGGK GGEDESVTLK SCTRRKTDSI EKRFCFDVEA VDRPGVITMQ ALSEEDRRLW 360
MEAMDGREPV YNSNKDSQSE GTAQLDSIGF SIIRKCIHAV ETRGINEQGL YRIVGVNSRV 420
QKLLSVLMDP KAASETETDI CAEWEIKTVT SALKTYLRML PGPLMMYQFQ RSFIKAAKLE 480
NQETRVSEIH SLVHRLPEKN RQMLQLLMNH LANVANNHKQ NLMTVANLGV VFGPTLLRPQ 540
EETVAAIMDI KFQNIVIEIL IENHEKIFNT VPDVPLTNAQ LHLSRKKSSD SKPPSCSERP 600
LTLFHAVPST EKQEQRNSII NSSLESVSSS ANSILNSSSS LQPNMNFSDP SLDVVKPTRP 660
NSLPPNPSPT SPLSPSWPMF SAPSSPMPTS STSSDSSPIR PEEVVHEDSS TPFRKAKALY 720
ACKAEHDSEL SFTAGTVFDN GLMGDTVSGN KMEEDRGRRQ Y 761 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0046847; P:filopodium assembly; IEA:InterPro.
 GO:0043547; P:positive regulation of GTPase activity; IEA:GOC.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR013606; IRSp53/MIM_homology_IMD.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR008936; Rho_GTPase_activation_prot.
 IPR000198; RhoGAP_dom. 
Pfam
 PF08397; IMD
 PF00620; RhoGAP 
SMART
 SM00233; PH
 SM00324; RhoGAP 
PROSITE
 PS50003; PH_DOMAIN
 PS50238; RHOGAP 
PRINTS