CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031333
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chromatin assembly factor 1 subunit B 
Protein Synonyms/Alias
 cDNA FLJ50264, highly similar to Homo sapiens membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) (MPP7), mRNA 
Gene Name
 MPP7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
262GLNELKRKLLISDTQubiquitination[1]
308ETDVQNNKFIEYGEYubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 374 AA 
Protein Sequence
MPEDIDDEED SVKIIRLVKN REPLGATIKK DEQTGAIIVA RIMRGGAADR SGLIHVGDEL 60
REVNGIPVED KRPEEIIQIL AQSQGAITFK IIPGSKEETP SKEGKMFIKA LFDYNPNEDK 120
AIPCKEAGLS FKKGDILQIM SQDDATWWQA KHEADANPRA GLIPSKHFQE RRLALRRPEI 180
LVQPLKVSNR KSSGFRKSFR LSRKDKKTNK SMYECKKSDQ YDTADVPTYE EVTPYRRQTN 240
EKYRLVVLVG PVGVGLNELK RKLLISDTQH YGVTVPHTTR ARRSQESDGV EYIFISKHLF 300
ETDVQNNKFI EYGEYKNNYY GTSIDSVRSV LAKNKVCLLD VQPHGPWFLL PLMAVPWGAK 360
PPNARMTCGS PLDL 374 
Gene Ontology
  
Interpro
 IPR008144; Guanylate_kin.
 IPR008145; Guanylate_kin/L-typ_Ca_channel.
 IPR020590; Guanylate_kinase_CS.
 IPR027417; P-loop_NTPase.
 IPR001478; PDZ.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 
Pfam
 PF00625; Guanylate_kin
 PF00595; PDZ
 PF07653; SH3_2 
SMART
 SM00072; GuKc
 SM00228; PDZ
 SM00326; SH3 
PROSITE
 PS00856; GUANYLATE_KINASE_1
 PS50052; GUANYLATE_KINASE_2
 PS50106; PDZ
 PS50002; SH3 
PRINTS
 PR00452; SH3DOMAIN.