UniProt Accession

 MATN2_MOUSE; O08746; E9QPK9; Q8R542 

Genbank Protein ID

 U69262; AF358844; AF358831; AF358832; AF358833; AF358834; AF358835; AF358836; AF358837; AF358838; AF358839; AF358840; AF358841; AF358842; AF358843; AC126028; AC133101; AC144632 

Genbank Nucleotide ID

 AAC53163.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1; AAM11539.1 

Protein Name

 Matrilin-2 

Protein Synonyms/Alias

  

Gene Name

 Matn2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
796	MYAVGVGKAIEEELQ	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Involved in matrix assembly (By similarity). 

Sequence Annotation

 DOMAIN 57 232 VWFA 1.
 DOMAIN 238 278 EGF-like 1.
 DOMAIN 279 319 EGF-like 2.
 DOMAIN 320 360 EGF-like 3.
 DOMAIN 361 401 EGF-like 4.
 DOMAIN 402 442 EGF-like 5.
 DOMAIN 443 483 EGF-like 6.
 DOMAIN 484 524 EGF-like 7.
 DOMAIN 525 565 EGF-like 8.
 DOMAIN 566 606 EGF-like 9.
 DOMAIN 607 647 EGF-like 10.
 DOMAIN 655 830 VWFA 2.
 CARBOHYD 221 221 N-linked (GlcNAc...) (Potential).
 CARBOHYD 890 890 N-linked (GlcNAc...) (Potential).
 DISULFID 242 253 By similarity.
 DISULFID 249 262 By similarity.
 DISULFID 264 277 By similarity.
 DISULFID 283 294 By similarity.
 DISULFID 290 303 By similarity.
 DISULFID 305 318 By similarity.
 DISULFID 324 335 By similarity.
 DISULFID 331 344 By similarity.
 DISULFID 346 359 By similarity.
 DISULFID 365 376 By similarity.
 DISULFID 372 385 By similarity.
 DISULFID 387 400 By similarity.
 DISULFID 406 417 By similarity.
 DISULFID 413 426 By similarity.
 DISULFID 428 441 By similarity.
 DISULFID 447 458 By similarity.
 DISULFID 454 467 By similarity.
 DISULFID 469 482 By similarity.
 DISULFID 488 499 By similarity.
 DISULFID 495 508 By similarity.
 DISULFID 510 523 By similarity.
 DISULFID 529 540 By similarity.
 DISULFID 536 549 By similarity.
 DISULFID 551 564 By similarity.
 DISULFID 570 581 By similarity.
 DISULFID 577 590 By similarity.
 DISULFID 592 605 By similarity.
 DISULFID 611 622 By similarity.
 DISULFID 618 631 By similarity.
 DISULFID 633 646 By similarity.  

Keyword

 Alternative splicing; Coiled coil; Complete proteome; Disulfide bond; EGF-like domain; Glycoprotein; Reference proteome; Repeat; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 956 AA 

Protein Sequence

Gene Ontology

 GO:0005604; C:basement membrane; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0007411; P:axon guidance; IGI:MGI.
 GO:0031104; P:dendrite regeneration; IMP:MGI.
 GO:0008347; P:glial cell migration; IDA:MGI.
 GO:0001764; P:neuron migration; IDA:MGI.
 GO:0048678; P:response to axon injury; IMP:MGI. 

Interpro

 IPR000742; EG-like_dom.
 IPR001881; EGF-like_Ca-bd.
 IPR013032; EGF-like_CS.
 IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
 IPR009030; Growth_fac_rcpt_N_dom.
 IPR019466; Matrilin_coiled-coil_trimer.
 IPR002035; VWF_A. 

Pfam

 PF07645; EGF_CA
 PF10393; Matrilin_ccoil
 PF00092; VWA 

SMART

 SM00181; EGF
 SM00327; VWA 

PROSITE

 PS00010; ASX_HYDROXYL
 PS01186; EGF_2
 PS50026; EGF_3
 PS50234; VWFA 

PRINTS