| Tag | Content |
|---|
| CPLM ID | CPLM-020014 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative ATP-dependent RNA helicase DHX30 |
Protein Synonyms/Alias | DEAH box protein 30 |
Gene Name | Dhx30 |
Gene Synonyms/Alias | Helg |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 658 | YLEDILAKLGKHQYP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Associates with mitochondrial DNA (By similarity). Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity). |
Sequence Annotation | DOMAIN 76 144 DRBM.
DOMAIN 467 635 Helicase ATP-binding.
DOMAIN 677 850 Helicase C-terminal.
NP_BIND 480 487 ATP (By similarity).
MOTIF 582 585 DEAH box. |
Keyword | Alternative splicing; ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase; Mitochondrion; Mitochondrion nucleoid; Nucleotide-binding; Phosphoprotein; Reference proteome; RNA-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1217 AA |
Protein Sequence | MAAARRLMAL AAGVSPRLRP PDPLVASGRQ GCSRGFSSSF VRSDGTQEAA EVESEVAPSE 60
PGEGDGSMVN ASRDLLKEFP QPKNLLNSVI GRALGISHAK DKLVYVHTNG PKKKKVTLHI 120
KWPKSVEVEG YGSKKIDAER QAAAAACQLF KGWGLLGPRN ELFDAAKYRV LADRFGSPAD 180
SWWRPEPTMP PTSWRQLNPE NIRPGGPAGL SRSLGREEEE DEEEELEEGT IDVTEFLSMT 240
QQDSHNPLRD SRGGSFEMTD DDSAIRALTQ FPLPKNLLAK VIQIATSSST AKNLMQFHTV 300
GTKTKLATLT LLWPCPMTFV AKGRRKAEAE NKAAALACKK LKSLGLVDRN NEPLTHAMYN 360
LASLRELGET QRRPCTIQVP EPILRKIEAF LSHYPVDSSW ISPELRLQSD DILPLGKDSG 420
PLSDPITGKP YMPLSEAEEV RLSQSLLELW RRRGPIWQEA PQLPVDPHRD TILSAIEQHP 480
VVVISGDTGC GKTTRIPQLL LERYVTEGRG ARCNVIITQP RRISAVSVAQ RVSHELGPSL 540
RRNVGFQVRL ESKPPARGGA LLFCTVGILL RKLQSNPSLE GVSHVIVDEV HERDVNTDFL 600
LILLKGLQRL NPALRLVLMS ATGDNERFSR YFGGCPVIKV PGFMYPVKEH YLEDILAKLG 660
KHQYPHRHRH HESEDECALD LDLVTDLVLH IDARGEPGGI LCFLPGWQEI KGVQQRLQEA 720
LGMHESKYLI LPVHSNIPMM DQKAIFQQPP LGVRKIVLAT NIAETSITVN DIVHVVDSGL 780
HKEERYDLKT KVSCLETVWV SRANVIQRRG RAGRCQSGFA YHLFPRSRLE KMVPFQVPEI 840
LRTPLENLVL QAKIHMPEKT AVEFLSKAVD SPNIKAVDEA VILLQEIGVL DQREYLTTLG 900
QRLAHISTDP RLAKAIVLAA IFRCLHPLLV VVSCLTRDPF SSSLQNRAEV DKVKALLSHD 960
SGSDHLAFVR AVAGWEEVLR WQDRTSRENY LEENLLYAPS LRFIHGLIKQ FSENIYEAFL 1020
VGKPSDCTLP SAQCNEYSEE EELVKGVLMA GLYPNLIQVR QGKVTRQGKF KPNSVTYRTK 1080
SGNILLHKST INREATRLRS RWLTYFMAVK SNGSVFVRDS SQVHPLAVLL LTDGDVHIRD 1140
DGRRATISLS DSDLLRLEGD SRTVRLLREF RRALGRMVER SLRSELAALP LSVQQEHGQL 1200
LALLAELLRG PCGSFDMRKT ADD 1223 |
Gene Ontology | GO:0042645; C:mitochondrial nucleoid; ISS:UniProtKB. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro. GO:0003682; F:chromatin binding; ISS:UniProtKB. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |